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Titolo:
TRANSMISSION OF THE EECT OF AN ANTIFUNGAL AGENT WITHIN A SINGLE HYPHA
Autore:
OH KB; MATSUOKA H; JING W; YAMAMOTO A; KURATA H;
Indirizzi:
TOKYO UNIV AGR & TECHNOL,FAC TECHNOL,DEPT BIOTECHNOL,2-24-16 NAKAMACHI KOGANEI TOKYO 184 JAPAN TOKYO UNIV AGR & TECHNOL,FAC TECHNOL,DEPT BIOTECHNOL KOGANEI TOKYO 184 JAPAN HIDAN CO LTD,DIV RES & DEV KASHIWA CHIBA 277 JAPAN TOKYO KEMBIKYOIN FDN,CHIYODA KU TOKYO 102 JAPAN
Titolo Testata:
Applied microbiology and biotechnology
fascicolo: 3-4, volume: 44, anno: 1995,
pagine: 473 - 478
SICI:
0175-7598(1995)44:3-4<473:TOTEOA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
DYNAMIC GROWTH-PROCESS; SUSCEPTIBILITY TEST; ANALYZING SYSTEM; MACRODILUTION; YEASTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
K.B. Oh et al., "TRANSMISSION OF THE EECT OF AN ANTIFUNGAL AGENT WITHIN A SINGLE HYPHA", Applied microbiology and biotechnology, 44(3-4), 1995, pp. 473-478

Abstract

A micro-compartment culture method was devised in which a single hypha of Rhizopus stolonifer growing on an agar section traversed an antifungal non-diffusible barrier to another agar section; thus the local environment of the distal or proximal part of the hypha could be controlled independently. The responses in terms of hyphal extension of the test fungus to local application of amphotericin B in this culture system were estimated by using an automatic analysing system. After hyphae had traversed the barrier, distal application of amphotericin B caused no appreciable effect on the proximal hyphae. In contrast, proximalapplication of amphotericin B caused inhibition of the extension of distal hyphae. The reversal of polarized cytoplasmic streaming also occurred during the inhibition of distal hyphal extension. The extents ofinhibition of the distal hyphal extension and the cytoplasmic streaming were dependent upon the hyphal distance between the amphotericin B application site and the hyphal tip. These results show that the effect of an antifungal agent on a hypha depends on the region of the hyphaexposed. Cytoplasmic streaming may play key role in the transmission of antifungal effects within a single hypha.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:34:18