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Titolo:
EVALUATION OF MTX 5-FU SEQUENTIAL CHEMOTHERAPY UTILIZED MTT ASSAY FORGASTROINTESTINAL CANCER/
Autore:
TANI M; TANIMURA H; YAMAUE H; HOTTA T; IWAHASHI M; TERASAWA H; NAKAMORI M; SHONO Y; NISHIMOTO N;
Indirizzi:
WAKAYAMA SCH MED,DEPT SURG 2,27 SHICHIBANCHO WAKAYAMA 640 JAPAN WAKAYAMA SCH MED,DEPT SURG 2 WAKAYAMA 640 JAPAN
Titolo Testata:
Oncology Reports
fascicolo: 1, volume: 3, anno: 1996,
pagine: 41 - 43
SICI:
1021-335X(1996)3:1<41:EOM5SC>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLORIMETRIC ASSAY; INVITRO CHEMOSENSITIVITY; ANTICANCER DRUGS; CYTO-TOXICITY; TUMOR-CELLS; 5-FLUOROURACIL; ADENOCARCINOMA; METHOTREXATE;
Keywords:
MTT ASSAY; METHOTREXATE; 5-FLUOROURACIL; BIOCHEMICAL MODULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
M. Tani et al., "EVALUATION OF MTX 5-FU SEQUENTIAL CHEMOTHERAPY UTILIZED MTT ASSAY FORGASTROINTESTINAL CANCER/", Oncology Reports, 3(1), 1996, pp. 41-43

Abstract

Fresh human gastrointestinal cancer cells are more resistant to anticancer drugs compared to other cancer cells, and the selection of anticancer drugs for cancer chemotherapy is important. In the present study, it is demonstrated that MTX enhanced the chemosensitivity of 5-FU, especially, in the tumor cells with less than 70% inhibition ratio by the MTT assay. It has been reported that MTX/5-FU sequential chemotherapy was one of the effective chemotherapies against gastric cancer and colon cancer, and it is possible to anticipate the efficacy of MTX/5-FU sequential chemotherapy by the MTT assays.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:52:49