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Titolo:
ISOSTERIC REPLACEMENT OF THE INDOLE NUCLEUS BY BENZOTHIOPHENE IN A SERIES OF PYRIDO[2,3-B]INDOLES WITH POTENTIAL ANXIOLYTIC ACTIVITY
Autore:
BLACKBURN TP; DAVIES DT; FORBES IT; HAYWARD CJ; JOHNSON CN; MARTIN RT; PIPER DC; THOMAS DR; THOMPSON M; UPTON N; WARD RW;
Indirizzi:
SMITHKLINE BEECHAM PHARMACEUT,NEW FRONTIERS SCI PK,3RD AVE HARLOW CM19 5AW ESSEX ENGLAND SMITHKLINE BEECHAM PHARMACEUT HARLOW CM19 5AW ESSEX ENGLAND
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 22, volume: 5, anno: 1995,
pagine: 2589 - 2592
SICI:
0960-894X(1995)5:22<2589:IROTIN>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINDING; CHLORIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
T.P. Blackburn et al., "ISOSTERIC REPLACEMENT OF THE INDOLE NUCLEUS BY BENZOTHIOPHENE IN A SERIES OF PYRIDO[2,3-B]INDOLES WITH POTENTIAL ANXIOLYTIC ACTIVITY", Bioorganic & medicinal chemistry letters, 5(22), 1995, pp. 2589-2592

Abstract

Isosteric replacement of the indole nucleus in a series of pyrido[2,3-b]indoles e.g. 1 and 2 has provided potent GABA(A) modulators with potential anxiolytic activity. Both benzothiophene and cycloalkyl fused heterocyclic ring systems are acceptable moieties.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 12:04:25