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Titolo:
ASSOCIATION OF MALIGNANT BRAIN-TUMORS AND CANCERS OF OTHER SITES
Autore:
AHSAN H; NEUGUT AI; BRUCE JN;
Indirizzi:
COLUMBIA UNIV COLL PHYS & SURG,SCH PUBL HLTH,DIV ONCOL,630 W 168TH STNEW YORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,SCH PUBL HLTH,DIV ONCOL NEW YORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,DEPT MED NEW YORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,DEPT NEUROL SURG NEW YORK NY 10032
Titolo Testata:
Journal of clinical oncology
fascicolo: 12, volume: 13, anno: 1995,
pagine: 2931 - 2935
SICI:
0732-183X(1995)13:12<2931:AOMBAC>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOS-ANGELES COUNTY; NONOCCUPATIONAL RISK INDICATORS; HUMAN BLADDER-CANCER; NERVOUS-SYSTEM; OCCUPATIONAL RISKS; COLORECTAL-CANCER; NEW-ZEALAND; MENINGIOMAS; CHILDHOOD; MORTALITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
57
Recensione:
Indirizzi per estratti:
Citazione:
H. Ahsan et al., "ASSOCIATION OF MALIGNANT BRAIN-TUMORS AND CANCERS OF OTHER SITES", Journal of clinical oncology, 13(12), 1995, pp. 2931-2935

Abstract

Purpose: We conducted an exploratory study of brain tumors that occurred as a second primary malignancy to identify potential risk factors for brain tumors.Methods: Using data from the Surveillance, Epidemiology, and End Results (SEER) Program, we calculated the sex-specific standardized incidence ratio (SIR), adjusted to age and rime period, as an estimate of the relative risk (RR) of developing a second primary brain tumor following other cancers. Results: We found an elevated RR ofbrain tumors after bladder cancer in both men (RR, 1.7; 95% confidence interval [CI], 1.2 to 2.3) and women (RR, 1.7; 95% CI, 0.8 to 3.2); this effect was present for both astrocytoma and glioblastoma multiforme. Elevated RRs of brain tumors were also found after sarcoma (RR, 4.4; 95% CI, 1.8 to 9.0) and leukemia (RR, 2.9; 95% CI, 1.6 to 4.8) in men, and after colorectal cancer (RR, 1.8; 95% CI, 1.3 to 2.4) and endometrial cancer (RR, 1.4; 95% CI, 1.0 to 1.9) in women. The highest RR observed in this study was for CNS lymphoma following any first primary malignancy in men (RR, 7.9; 95% CI, 5.5 to 11.0). Conclusion: The associations of brain tumors with bladder, colorectal, and endometrial cancers in women, and an increased occurrence of CNS lymphoma as a second malignancy in men, are new findings that have not been described previously. (C) 1995 by American Society of Clinical Oncology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:43:59