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Titolo:
SKELETAL-MUSCLE PATHOLOGY IN SYSTEMIC-SCLEROSIS
Autore:
CALORE EE; CAVALIERE MJ; PEREZ NM; TAKAYASU V; WAKAMATSU A; KISS MH;
Indirizzi:
INST INFECTOL EMILIO RIBAS,SECAO ANAT PATOL,AV DR ARNALDO 165 BR-01246001 SAO PAULO BRAZIL FMUSP,DEPT PATOL,PATOL MOLEC LAB SAO PAULO BRAZIL INST ADOLFO LUTZ REGISTRO SAO PAULO BRAZIL HOSP UNIV SAO PAULO SAO PAULO BRAZIL FMUSP,INST CRIANCA SAO PAULO BRAZIL
Titolo Testata:
Journal of rheumatology
fascicolo: 12, volume: 22, anno: 1995,
pagine: 2246 - 2249
SICI:
0315-162X(1995)22:12<2246:SPIS>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-ADHESION MOLECULE; N-CAM; EXPRESSION;
Keywords:
SYSTEMIC SCLEROSIS; MUSCLE PATHOLOGY; NEUROGENIC ATROPHY; MUSCLE DISEASES; NEURAL CELL ADHESION MOLECULES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
E.E. Calore et al., "SKELETAL-MUSCLE PATHOLOGY IN SYSTEMIC-SCLEROSIS", Journal of rheumatology, 22(12), 1995, pp. 2246-2249

Abstract

Objective. Systemic sclerosis (SSc) is characterized by abnormal deposition of collagen in the skin and by visceral involvement. Muscle weakness is a relatively frequent complication of SSe, although severity varies. We studied muscle pathology in patients with SSe with progressive muscle involvement. Methods. We performed histochemical and immunohistochemical investigations to detect neural cell adhesion molecule (NCAM). Results. Five of the 6 cases of SSe expressed NCAM in atrophic angulated fibers (some fibers stained heavily with oxidative enzymes). Conclusion. Neurogenic involvement in SSc is more frequent than reported.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/02/20 alle ore 22:17:03