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Titolo:
MODULATORY FUNCTIONS OF NEUROTRANSMITTERS IN THE STRIATUM - ACH DOPAMINE/NMDA INTERACTIONS/
Autore:
DICHIARA G; MORELLI M; CONSOLO S;
Indirizzi:
UNIV CAGLIARI,DEPT TOXICOL CAGLIARI ITALY UNIV CAGLIARI,CNR,CTR NEUROPHARMACOL CAGLIARI ITALY IST RIC FARMACOL MARIO NEGRI MILAN ITALY
Titolo Testata:
Trends in neurosciences
fascicolo: 6, volume: 17, anno: 1994,
pagine: 228 - 233
SICI:
0166-2236(1994)17:6<228:MFONIT>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-FOS EXPRESSION; ENDOGENOUS ACETYLCHOLINE-RELEASE; MONOAMINE-DEPLETED MICE; DOPAMINE RECEPTOR GENE; FREELY MOVING RATS; CHOLINERGIC NEURONS; BASAL GANGLIA; PHENOTYPICAL CHARACTERIZATION; 6-HYDROXYDOPAMINE MODEL; STRIATOPALLIDAL NEURONS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
81
Recensione:
Indirizzi per estratti:
Citazione:
G. Dichiara et al., "MODULATORY FUNCTIONS OF NEUROTRANSMITTERS IN THE STRIATUM - ACH DOPAMINE/NMDA INTERACTIONS/", Trends in neurosciences, 17(6), 1994, pp. 228-233

Abstract

The striatum is viewed as a structure performing fast neurotransmitter-mediated operations through somato-topically organized projections to medium-size spiny neurons. This view is contrasted with another viewthat depicts the striatum as a site of diffuse modulatory influences mediated by cholinergic interneurons and by dopamine and N-methyl-D-aspartate receptors. These two operational and organizational modes bothcontribute, through their mutual interaction, to the function of basal ganglia. Detailed knowledge of the neural mechanisms by which such interactions take place and are expressed into behaviour, can provide new insight into the physiopathology and new clues for therapy of disorders of basal ganglia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 22:11:25