Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE ENDOCRINOLOGY OF THE MENOPAUSAL TRANSITION - A CROSS-SECTIONAL STUDY OF A POPULATION-BASED SAMPLE
Autore:
BURGER HG; DUDLEY EC; HOPPER JL; SHELLEY JM; GREEN A; SMITH A; DENNERSTEIN L; MORSE C;
Indirizzi:
KEY CTR WOMENS HLTH SOC,211 GRATTAN ST CARLTON VIC 3053 AUSTRALIA KEY CTR WOMENS HLTH SOC CARLTON VIC 3053 AUSTRALIA PRINCE HENRYS INST MED RES CLAYTON VIC AUSTRALIA UNIV MELBOURNE,DEPT PUBL HLTH & COMMUNITY MED CARLTON VIC AUSTRALIA LA TROBE UNIV,CTR STUDY SEXUALLY TRANSMITTED DIS CARLTON VIC AUSTRALIA QUEENSLAND INST MED RES,BANCROFT CTR BRISBANE QLD 4006 AUSTRALIA
Titolo Testata:
The Journal of clinical endocrinology and metabolism
fascicolo: 12, volume: 80, anno: 1995,
pagine: 3537 - 3545
SICI:
0021-972X(1995)80:12<3537:TEOTMT>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOLLICLE-STIMULATING-HORMONE; PITUITARY-OVARIAN FUNCTION; LUTEINIZING-HORMONE; BINDING GLOBULIN; WOMEN; ESTRADIOL; INHIBIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
H.G. Burger et al., "THE ENDOCRINOLOGY OF THE MENOPAUSAL TRANSITION - A CROSS-SECTIONAL STUDY OF A POPULATION-BASED SAMPLE", The Journal of clinical endocrinology and metabolism, 80(12), 1995, pp. 3537-3545

Abstract

In a study of the endocrinology of the perimenopausal years, levels of serum FSH, estradiol (E(2)), immunoreactive inhibin (INH), testosterone, and sex hormone-binding globulin were measured in a population-based sample of 380 women (mean age, 49.4 yr; range, 45.6-56.9 yr). Subjects were divided into women who reported continuing regular menstrualcycles (27%; group I), a change in menstrual flow without a change infrequency (23%; group II), a change in frequency but no change in flow (9%; group III), changes in both frequency and flow (28%; group IV),and at least 3 months since their last menstrual period (13%; group V). After adjusting for age and body mass index, the geometric mean FSHincreased across menstrual groups and, compared with group I, was 53%higher in group IV (P < 0.0005) and 253% higher in group V (P < 0.0001). Age- and body mass index-adjusted geometric means for E(2) and INHin group V were 54% and 53% of those in group 1, respectively (P < 0.005, P < 0.0001). Women in group V who did not have a menstrual periodin the next year had higher FSH and lower E(2) and INH levels than those who subsequently went on to have at least one more menstrual period (P < 0.05). FSH was negatively correlated with E(2) (r = -0.30) and INH (r = -0.39), whereas INH was positively correlated with E(2) (r = 0.45). We conclude that an increase in serum FSH and decreases in E(2)and INH are the major endocrine changes associated cross-sectionally with the menopausal transition.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/08/20 alle ore 23:20:03