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Titolo:
COMPARISON OF DYNAMIC AND PASSIVE MEASUREMENTS OF RESPIRATORY MECHANICS IN VENTILATED NEWBORN-INFANTS
Autore:
KUGELMAN A; KEENS TG; DELEMOS R; DURAND M;
Indirizzi:
UNIV SO CALIF,LOS ANGELES CTY MED CTR,WOMENS HOSP,ROOM L-919,1240 N MISS RD LOS ANGELES CA 90033 UNIV SO CALIF,LOS ANGELES CTY MED CTR,WOMENS HOSP LOS ANGELES CA 90033 CHILDRENS HOSP LOS ANGELES,DIV NEONATOL & PEDIAT PULM LOS ANGELES CA 90027
Titolo Testata:
Pediatric pulmonology
fascicolo: 4, volume: 20, anno: 1995,
pagine: 258 - 264
SICI:
8755-6863(1995)20:4<258:CODAPM>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIRTH-WEIGHT INFANTS; CHRONIC LUNG-DISEASE; ESOPHAGEAL PRESSURE; PULMONARY MECHANICS; INTUBATED INFANTS; PREMATURE-INFANTS; DISTRESS SYNDROME; PRETERM INFANTS; SURFACTANT; ACCURACY;
Keywords:
DYNAMIC PULMONARY MECHANICS; PASSIVE PULMONARY MECHANICS; RESPIRATORY SYSTEM COMPLIANCE; RESPIRATORY SYSTEM RESISTANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
A. Kugelman et al., "COMPARISON OF DYNAMIC AND PASSIVE MEASUREMENTS OF RESPIRATORY MECHANICS IN VENTILATED NEWBORN-INFANTS", Pediatric pulmonology, 20(4), 1995, pp. 258-264

Abstract

Pulmonary mechanics may differ in intubated and ventilated infants depending on whether they are measured by a dynamic or passive method. The objective of this study was to compare respiratory mechanics measured by a dynamic technique with those obtained by a single-breath occlusion technique in ventilated newborn infants. Thirty-one preterm and 15 term infants (mean +/- SD: gestational age, 29.3 +/- 2.3 and 39.5 +/- 1.4 weeks; birth weight, 1.2 +/- 0.5 and 3.4 +/- 0.4 kg; postnatal age, 12 +/- 13 and 5 +/- 4 days, respectively) were studied. Flows weremeasured through a pneumotachometer placed between the endotracheal tube and the ventilator circuit: tidal volume by integration of flow, and airway pressure directly with a pressure transducer. Airway occlusion was performed with a Neonatal Occlusion Valve (Bicore pulmonary monitor) at the end of inspiration, and the following relaxed exhalation was analyzed to give passive respiratory system compliance (C-rs) and resistance (R(rs)). These values were compared with dynamic respiratory system compliance (C-dyn) and dynamic expiratory resistance (R(e)) obtained with the PEDS system (P) within 1 hour, without an esophageal balloon and on the same ventilator settings. Dynamic respiratory system compliance and resistance measured with the PEDS and the Bicore systems did not differ significantly and were well correlated. Mean C-dyn (P) values in preterm and term infants were 77% and 77% of C-rs; the equation of the regression line was C-dyn = 0.75 C-rs + 0.02 and C-dyn = 0.78 C-rs - 0.02; and standard error of the estimate (SEE) was 0.2 and 0.3 mL/cmH(2)O with a correlation coefficient (r) of 0.89 and 0.89 (P < 0.0001), respectively. The mean R(e) (P) values in preterm and term infants were 68% and 64% of R(rs), and the equation of the regression line was R(e) = 0.3 R(rs) + 63 and R(e) = 0.5 R(rs) + 20, with SEE of 25 and 20 cmH(2)O/L/sec, and r of 0.65 and 0.69 (P < 0.0001, P < 0.005), respectively. The two methods are non-invasive and were well tolerated. We conclude that passive and dynamic respiratory compliance and resistance measured in intubated infants are highly correlated, although the values measured by the passive technique are higher than those obtained by the dynamic technique. (C) 1995 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 08:25:27