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Titolo:
SACCADIC DISTRACTIBILITY IN COCAINE-DEPENDENT PATIENTS - A PRELIMINARY LABORATORY EXPLORATION OF THE COCAINE-OCD HYPOTHESIS
Autore:
ROSSE RB; MCCARTHY MF; ALIM TN; DEUTSCH SI;
Indirizzi:
VET AFFAIRS MED CTR,PSYCHIAT SERV,ROOM 3A154-116A,50 IRVING ST NW WASHINGTON DC 20422 VET AFFAIRS MED CTR,PSYCHIAT SERV WASHINGTON DC 20422 GEORGETOWN UNIV,SCH MED,DEPT PSYCHIAT WASHINGTON DC 20007 VET ADM NATL INST DRUG ABUSE,SUBST ABUSE RES UNIT WASHINGTON DC 20422 HOWARD UNIV,MED CTR,DEPT PSYCHIAT WASHINGTON DC 20060
Titolo Testata:
Drug and alcohol dependence
fascicolo: 1, volume: 35, anno: 1994,
pagine: 25 - 30
SICI:
0376-8716(1994)35:1<25:SDICP->2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSESSIVE-COMPULSIVE DISORDER; INDUCED PARANOIA; PSYCHOSIS; BEHAVIOR; MODEL; URGES;
Keywords:
COCAINE DEPENDENCE; OBSESSIVE-COMPULSIVE DISORDER; ANTISACCADE TASK; SUBSTANCE ABUSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
R.B. Rosse et al., "SACCADIC DISTRACTIBILITY IN COCAINE-DEPENDENT PATIENTS - A PRELIMINARY LABORATORY EXPLORATION OF THE COCAINE-OCD HYPOTHESIS", Drug and alcohol dependence, 35(1), 1994, pp. 25-30

Abstract

Epidemiologic Cachment Area Survey (ECAS) results suggest that cocaine abusing patients are at increased risk for the later development of Obsessive Compulsive Disorder (OCD), and a need for attention in laboratory and clinical research to the 'cocaine-OCD hypothesis' has been described. Analysis of the ECAS data, however, could not rule out the possibility of a 'distinctive OCD-like syndrome' related to cocaine use. Such an OCD-like syndrome in cocaine dependent individuals has been recently described, where some cocaine dependent patients compulsivelyforage for cocaine, especially after a cocaine binge. To further explore a possible relationship between cocaine dependence and OCD, the performance on an antisaccade task of 32 cocaine dependent individuals was compared to a group of 15 individuals without neuropsychiatric or substance abusing histories. OCD patients have been described as havinga greater frequency of reflexive glances (i.e., increased saccadic distractibility) during the antisaccade task than normals. No statistically significant differences in antisaccade performance were observed between the cocaine dependent patients and a normal comparison group. However, when the cocaine using group was divided into those endorsing and those not endorsing significant cocaine-induced compulsive foraging, statistically significant differences emerged. Cocaine-induced compulsive foragers had the poorest antisaccade performance. While the small sample sizes and the lack of an OCD control group limit the conclusions that can be drawn from the present study, the results seem to suggest that a cocaine-OCD link might be particularly relevant for those cocaine addicts endorsing compulsive foraging.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 14:54:43