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Titolo:
LHERMITTE-DUCLOS DISEASE AND GIANT MENINGIOMA AS MANIFESTATIONS OF COWDENS-DISEASE
Autore:
LINDBOE CF; HELSETH E; MYHR G;
Indirizzi:
UNIV TRONDHEIM HOSP,DEPT PATHOL N-7006 TRONDHEIM NORWAY UNIV TRONDHEIM HOSP,DEPT NEUROSURG N-7006 TRONDHEIM NORWAY UNIV TRONDHEIM HOSP,MR CTR N-7006 TRONDHEIM NORWAY
Titolo Testata:
Clinical neuropathology
fascicolo: 6, volume: 14, anno: 1995,
pagine: 327 - 330
SICI:
0722-5091(1995)14:6<327:LDAGMA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE HAMARTOMA;
Keywords:
COWDENS DISEASE; DYSPLASTIC GANGLIOCYTOMA OF THE CEREBELLUM; LHERMITTE-DUCLOS DISEASE; MENINGIOMA; MULTIPLE HAMARTOMA-NEOPLASIA SYNDROME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
C.F. Lindboe et al., "LHERMITTE-DUCLOS DISEASE AND GIANT MENINGIOMA AS MANIFESTATIONS OF COWDENS-DISEASE", Clinical neuropathology, 14(6), 1995, pp. 327-330

Abstract

A 43-year-old man with synchronous occurrence of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) and a giant meningioma with subcutaneous infiltration is reported. Subsequent examinationsrevealed typical manifestations of Cowden's disease (multiple hamartoma-neoplasia syndrome), i.e. mucocutaneous lesions and increased head circumference. Our findings support the view that there is a correlation between Lhermitte-Duclos disease and Cowden's disease. We conclude that all patients with Lhermitte-Duclos disease should be thoroughly examined with regard to Cowden's disease, which necessitates lifelong follow-up with screening for neoplasia in various organ systems. The occurrence of both Lhermitte-Duclos disease and a meningioma as part of the Cowden's symptom complex is very rare and to our knowledge only one case with this combination of lesions has previously been reported.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 11:23:41