Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
HUMAN-HERPESVIRUS-6 POLYMERASE CHAIN-REACTION FINDINGS IN HUMAN-IMMUNODEFICIENCY-VIRUS ASSOCIATED NEUROLOGICAL DISEASE AND MULTIPLE-SCLEROSIS
Autore:
LIEDTKE W; MALESSA R; FAUSTMANN PM; EISHUBINGER AM;
Indirizzi:
YESHIVA UNIV ALBERT EINSTEIN COLL MED,1300 MORRIS PK AVE BRONX NY 10461 ESSEN UNIV HOSP,DEPT NEUROL D-45122 ESSEN GERMANY UNIV BONN,INST MED MICROBIOL & IMMUNOL D-53105 BONN GERMANY
Titolo Testata:
Journal of neurovirology
fascicolo: 3-4, volume: 1, anno: 1995,
pagine: 253 - 258
SICI:
1355-0284(1995)1:3-4<253:HPCFIH>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBROSPINAL-FLUID; EXANTHEM-SUBITUM; CELL-LINES; INFECTION; HHV-6; AIDS; PCR; DISORDERS; TROPISM; HBLV;
Keywords:
MESH, HHV6; PCR; NEURO-AIDS; ENCEPHALOMYELITIS DISSEMINATA (ED); CEREBROSPINAL FLUID (CSF); IMMUNOFLUORESCENCE SEROLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
W. Liedtke et al., "HUMAN-HERPESVIRUS-6 POLYMERASE CHAIN-REACTION FINDINGS IN HUMAN-IMMUNODEFICIENCY-VIRUS ASSOCIATED NEUROLOGICAL DISEASE AND MULTIPLE-SCLEROSIS", Journal of neurovirology, 1(3-4), 1995, pp. 253-258

Abstract

A role for human herpesvirus 6 (HHV6) in the neurological complications associated with infection by human immunodeficiency virus (neuro-AIDS) and during multiple sclerosis (MS) is not known. For the present study, an improved PCR and immunofluorescence serology method were applied to sera and cerebrospinal fluid (CSF) from 27 neuro-AIDS, 36 MS and 24 noninflammatory control patients. HHV6 DNA was present in 30-40% of the cellular CSF from all groups. In the acellular CSF, HHV6 could be detected in four of 36 MS, 2 of 27 neuro-AIDS and none of the control patients. HHV6 IgG was present in one of 27 neuro-AIDS, and one of 36 MS patients. HHV6 IgG was present in all patients. There was no correlation between clinical features and HHV6 PCR findings or HHV6 antibodies. The significance of the present documentation of HHV6 DNA in the acellular CSF from a minority of MS and neuro-AIDS patients remains to be determined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:25:48