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Titolo:
USE OF INTRAVENOUS IMMUNE GLOBULIN IN THE THERAPY OF CHILDREN WITH RHEUMATOLOGICAL DISEASES
Autore:
ROIFMAN CM;
Indirizzi:
HOSP SICK CHILDREN,DIV ALLERGY IMMUNOL,555 UNIV AVE TORONTO ON M5G 1X8 CANADA
Titolo Testata:
Journal of clinical immunology
fascicolo: 6, volume: 15, anno: 1995, supplemento:, S
pagine: 42 - 51
SICI:
0271-9142(1995)15:6<42:UOIIGI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
JUVENILE RHEUMATOID-ARTHRITIS; GAMMA-GLOBULIN; SERUM GLOBULIN; DERMATOMYOSITIS; POLYMYOSITIS;
Keywords:
INTRAVENOUS IMMUNE GLOBULIN; DERMATOMYOSITIS; SYSTEMIC-ONSET JUVENILE RHEUMATOID ARTHRITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
C.M. Roifman, "USE OF INTRAVENOUS IMMUNE GLOBULIN IN THE THERAPY OF CHILDREN WITH RHEUMATOLOGICAL DISEASES", Journal of clinical immunology, 15(6), 1995, pp. 42-51

Abstract

Similarly, some patients with systemic juvenile rheumatoid arthritis continue to develop crippling arthritis despite the currently used modalities of therapy. We have used monthly infusions of intravenous immune globulin (2 g/kg/month) in patients with dermatomyositis or systemic juvenile rheumatoid arthritis who have not responded to traditional treatment. We show that intravenous immune globulin is beneficial in improving muscle strength and skin manifestations of dermatomyositis. In a similar fashion, intravenous immune globulin infusions were very effective in ameliorating systemic manifestations of systemic juvenile rheumatoid arthritis but less effective in controlling long-lasting arthritis (more than 1 year). We established prognostic criteria early after disease onset which predict the development of severe joint disease and should help in patient selection for future studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 15:01:14