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Titolo:
SYMPTOMS OF DENGUE FEVER IN RELATION TO HOST IMMUNOLOGICAL RESPONSE AND VIRUS SEROTYPE, PUERTO-RICO, 1990-1991
Autore:
COBRA C; RIGAUPEREZ JG; KUNO G; VORNDAM V;
Indirizzi:
SAN JUAN LABS,2 CALLE CASIA SAN JUAN PR 00921 JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH BALTIMORE MD 00000 CTR DIS CONTROL & PREVENT,NATL CTR INFECT DIS,DIV VECTOR BORNE INFECTDIS,DENGUE BRANCH SAN JUAN PR 00000 CTR DIS CONTROL & PREVENT,NATL CTR INFECT DIS,DIV VECTOR BORNE INFECTDIS FT COLLINS CO 80522
Titolo Testata:
American journal of epidemiology
fascicolo: 11, volume: 142, anno: 1995,
pagine: 1204 - 1211
SICI:
0002-9262(1995)142:11<1204:SODFIR>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIBODY-DEPENDENT ENHANCEMENT; LINKED IMMUNOSORBENT-ASSAY; HEMORRHAGIC-FEVER; SHOCK SYNDROME; RISK-FACTORS; PATHOGENESIS; DISEASE; INFECTIONS;
Keywords:
ARBOVIRUS INFECTIONS; DENGUE; DENGUE VIRUS; HEMORRHAGIC FEVERS, VIRAL; IMMUNOLOGICAL SURVEILLANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
C. Cobra et al., "SYMPTOMS OF DENGUE FEVER IN RELATION TO HOST IMMUNOLOGICAL RESPONSE AND VIRUS SEROTYPE, PUERTO-RICO, 1990-1991", American journal of epidemiology, 142(11), 1995, pp. 1204-1211

Abstract

The authors investigated the role of secondary immunologic response, virus serotype, age, and sex on the clinical manifestations of dengue fever in Puerto Rico. From surveillance data for 1990 and 1991, this study identified 3,926 laboratory-positive cases, including 889 for whom dengue immunologic status and symptoms could be ascertained. Of those, 622 cases were virologically confirmed, and 267 cases were serologically confirmed. More than 50% of all positive patients reported fever, chills, headache, eye pain, body pains, joint pains, nausea, vomiting, or skin rash. The frequency of reporting signs, symptoms, and hospitalization was significantly higher among persons with secondary infections diagnosed by serologic methods, Only rash was more common among those with primary infections, Symptom reporting increased with age; body pains, joint pains, and rash were significantly more frequently reported by female patients. No significant difference in symptom frequency was found among the virologically confirmed cases, comparing primary and secondary cases or infections due to different serotypes, The data for serologically confirmed cases suggest that in Puerto Rico the manifestations of dengue fever are, as with dengue hemorrhagic fever in Asia, more prominent among those who are experiencing secondary infections, and this effect may be more marked in the younger age groups.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 14:29:18