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Titolo:
A WAVE TRANSMISSION MODEL OF THE UMBILICOPLACENTAL CIRCULATION BASED ON HEMODYNAMIC MEASUREMENTS IN SHEEP
Autore:
HILL AA; SURAT DR; COBBOLD RSC; LANGILLE BL; MO LYL; ADAMSON SL;
Indirizzi:
MT SINAI HOSP,SAMUEL LUNENFELD RES INST,600 UNIV AVE,RM 138-P TORONTOON M5G 1X5 CANADA UNIV TORONTO,TORONTO HOSP RES INST,DEPT OBSTET & GYNECOL TORONTO ON M5G 1X5 CANADA UNIV TORONTO,TORONTO HOSP RES INST,INST BIOMED ENGN TORONTO ON M5G 1X5 CANADA SAMUEL LUNENFELD RES INST TORONTO ON M5G 1X5 CANADA
Titolo Testata:
American journal of physiology. Regulatory, integrative and comparative physiology
fascicolo: 5, volume: 38, anno: 1995,
pagine: 1267 - 1278
SICI:
0363-6119(1995)38:5<1267:AWTMOT>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
FETOPLACENTAL CIRCULATION; UMBILICAL ARTERIES; FLOW; IMPEDANCE;
Keywords:
WAVE PROPAGATION; ARTERIAL IMPEDANCE; FETUS; OVINE; PLACENTA; UMBILICAL ARTERY; TRANSMISSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
A.A. Hill et al., "A WAVE TRANSMISSION MODEL OF THE UMBILICOPLACENTAL CIRCULATION BASED ON HEMODYNAMIC MEASUREMENTS IN SHEEP", American journal of physiology. Regulatory, integrative and comparative physiology, 38(5), 1995, pp. 1267-1278

Abstract

Electrical analog models of the umbilical circulation were developed based on hemodynamic measurements in fetal sheep. The umbilical arterywas represented by a transmission line and the placenta by a resistive load. Model predictions of input impedance and pressure and flow waveforms agreed with in vivo measurements under baseline conditions, following placental embolization, and during angiotensin II infusion. A unique positive impedance phase observed at the heart rate frequency under baseline conditions was best explained by the unusual viscoelasticproperties of the umbilical arterial wall and small load reflections. Furthermore, a short, less vasoactive segment of the umbilical arteryin the retroperitoneal space had a large impact on the input impedance of the umbilical circulation, which was particularly apparent when the artery was constricted during angiotensin II infusion. The model indicated that reflections arising near the approximate location where the first arterial branches leave the main umbilical artery have a measurable impact on impedance spectra when load reflections are low.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 05:34:54