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Titolo:
EFFECTS OF EXPOSURE TO HYPOBARIC-HYPOXIA ON BODY-WEIGHT, MUSCULAR ANDHEMATOLOGICAL CHARACTERISTICS, AND WORK PERFORMANCE IN RATS
Autore:
TANAKA M; MIZUTA K; KOBA F; OHIRA Y; KOBAYASHI T; HONDA Y;
Indirizzi:
KAGOSHIMA IMMACULATE HEART UNIV,SCH NURSING SENDAI MIYAGI 895 JAPAN NATL INST FITNESS & SPORTS,DEPT PHYSIOL & BIOMECH KANOYA 89123 JAPAN TOKYO UNIV MERCANTILE MARINE,HLTH SCI CTR,KOTO KU TOKYO 135 JAPAN CHIBA UNIV,SCH MED,DEPT PHYSIOL CHIBA 260 JAPAN
Titolo Testata:
Japanese Journal of Physiology
fascicolo: 1, volume: 47, anno: 1997,
pagine: 51 - 57
SICI:
0021-521X(1997)47:1<51:EOETHO>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-ALTITUDE EXPOSURE; SKELETAL-MUSCLE; EXERCISE INTENSITY; SOLEUS MUSCLE; CAPACITY; ADAPTATIONS; METABOLISM; ENDURANCE; RESPONSES;
Keywords:
HYPOBARIC-HYPOXIA; SWIMMING PERFORMANCE; SKELETAL MUSCLE; ENZYME ACTIVITY; HEMATOLOGICAL PROFILES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
M. Tanaka et al., "EFFECTS OF EXPOSURE TO HYPOBARIC-HYPOXIA ON BODY-WEIGHT, MUSCULAR ANDHEMATOLOGICAL CHARACTERISTICS, AND WORK PERFORMANCE IN RATS", Japanese Journal of Physiology, 47(1), 1997, pp. 51-57

Abstract

The metabolic activities of skeletal muscles were studied in male rats exposed to hypobaric-hypoxia at about 550 Torr for 8h per day for 2 weeks. Rats were divided into three groups; control (normoxic control), diurnal hypoxic (DH) exposure, and nocturnal hypoxic (NH) exposure groups. The changes in body weight and daily diet intake of the NH group were lower than the other groups (p<0.01). The weights of fat in theabdominal cavity of both NH and DH groups were less than that of the control group. The red blood cell count, hemoglobin concentration, andhematocrit values were significantly increased in the hypoxic groups. The plasma glucose level in the NH group was significantly less than the control group (p<0.05). The lactate dehydrogenase/citrate synthase(LDH/CS) activity ratios in the skeletal muscle tended to be lower inboth hypoxic groups than in the control group. The swimming times to exhaustion at mild and high intensities that were measured after 2 weeks, loaded with a weight equivalent to 2.5% of the body weight, improved in the DH group. There were insignificant differences in the metabolic activity of skeletal muscles and blood characteristics between theNH and DH groups, but endurance swimming times in the DH group tendedto be improved as compared to the NH group. We conclude that the DH group became competent in endurance work, which is believed to be derived from the combined effects of increased O-2 transport capacity of the blood and enhanced O-2 utilization capability by mitochondrial enzyme activity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:35:49