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Titolo:
EXPRESSION AND FUNCTION OF DECAPENTAPLEGIC AND THICK VEINS DURING THEDIFFERENTIATION OF THE VEINS IN THE DROSOPHILA WING
Autore:
DECELIS JF;
Indirizzi:
UNIV CAMBRIDGE,DEPT GENET CAMBRIDGE CB2 4TH ENGLAND
Titolo Testata:
Development
fascicolo: 5, volume: 124, anno: 1997,
pagine: 1007 - 1018
SICI:
0950-1991(1997)124:5<1007:EAFODA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
TGF-BETA RECEPTOR; CELL-INTERACTIONS; GENE-EXPRESSION; NERVOUS-SYSTEM; IMAGINAL DISKS; NOTCH FUNCTION; I RECEPTORS; MELANOGASTER; PATTERN; FAMILY;
Keywords:
DECAPENTAPLEGIC; THICK VEINS; VEIN DIFFERENTIATION; CELL INTERACTIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
61
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Decelis, "EXPRESSION AND FUNCTION OF DECAPENTAPLEGIC AND THICK VEINS DURING THEDIFFERENTIATION OF THE VEINS IN THE DROSOPHILA WING", Development, 124(5), 1997, pp. 1007-1018

Abstract

The differentiation of the veins in the Drosophila wing involves the coordinate activities of several signal transduction pathways, including those mediated by the transmembrane receptors Torpedo and Notch. Inthis report, the role of the signalling molecule Decapentaplegic during vein differentiation has been analysed. It is shown that decapentaplegic is expressed in the pupal veins under the control of genes that establish vein territories in the imaginal disc. Decapentaplegic, acting through its receptor Thick veins, activates vein differentiation and restricts expression of both veinlet and the Notch-ligand Delta to the developing veins. Genetic combinations between mutations that increase or reduce Notch, veinlet and decapentaplegic activities suggest that the maintenance of the vein differentiation state during pupal development involves cross-regulatory interactions between these pathways.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 11:12:51