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Titolo:
EXHAUSTIVE PHYSICAL EXERCISE INCREASES FREQUENCY OF MICRONUCLEI
Autore:
SCHIFFL C; ZIERES C; ZANKL H;
Indirizzi:
UNIV KAISERSLAUTERN,DEPT HUMAN BIOL & HUMAN GENET D-67663 KAISERSLAUTERN GERMANY UNIV KAISERSLAUTERN,DEPT HUMAN BIOL & HUMAN GENET D-67663 KAISERSLAUTERN GERMANY
Titolo Testata:
Mutation research. Genetic toxicology and environmental mutagenesis
fascicolo: 2-3, volume: 389, anno: 1997,
pagine: 243 - 246
SICI:
1383-5718(1997)389:2-3<243:EPEIFO>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
DNA-DAMAGE; FREE-RADICALS; LYMPHOCYTES;
Keywords:
MICRONUCLEUS; DNA DAMAGE; PHYSICAL EXERCISE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
C. Schiffl et al., "EXHAUSTIVE PHYSICAL EXERCISE INCREASES FREQUENCY OF MICRONUCLEI", Mutation research. Genetic toxicology and environmental mutagenesis, 389(2-3), 1997, pp. 243-246

Abstract

Micronucleus (MN) tests were performed on PHA-stimulated blood lymphocytes of six healthy volunteers before and after two exhaustive sprints, causing lactate concentrations in the peripheral blood between 9.6 and 12.4 mmol/l. The number of micronuclei was significantly increasedafter 24-48 h in all six subjects. The mean of the total group increased from 37 MN per 3000 binucleated cells before exercise to 56 and 55MN 24 and 38 h after exercise, respectively. These differences were also significant. These results indicate that exhaustive physical exercise causes severe mutations at the chromosome level in blood lymphocytes.

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Documento generato il 21/09/20 alle ore 03:19:06