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Titolo:
A CASE OF DYSHORMONOGENETIC GOITER COMPLICATED WITH GROWTH-HORMONE DEFICIENCY
Autore:
KAJI M; TERASAKI A; NAKATO H; HATA I; YOKOTA T; FUKUMOTO M; HAMASAKI S;
Indirizzi:
SHIZUOKA CHILDRENS HOSP,DIV ENDOCRINOL & METAB,860 URUSHIYAMA SHIZUOKA 420 JAPAN KYOTO UNIV,SCH MED,DEPT PATHOL SHIZUOKA JAPAN HIKONE CITY HOSP,DEPT PEDIAT SHIZUOKA JAPAN HIKONE CITY HOSP,DEPT SURG SHIZUOKA JAPAN
Titolo Testata:
Acta Paediatrica Japonica Overseas Edition
fascicolo: 1, volume: 39, anno: 1997,
pagine: 83 - 87
SICI:
0374-5600(1997)39:1<83:ACODGC>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGENITAL HYPOTHYROIDISM;
Keywords:
DYSHORMONOGENETIC GOITER; FOLLICULAR ADENOMA; GROWTH HORMONE DEFICIENCY; HYPOTHYROIDISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
M. Kaji et al., "A CASE OF DYSHORMONOGENETIC GOITER COMPLICATED WITH GROWTH-HORMONE DEFICIENCY", Acta Paediatrica Japonica Overseas Edition, 39(1), 1997, pp. 83-87

Abstract

A 17-year-old male patient with dyshormonogenetic goiter complicated with follicular adenoma and growth hormone deficiency is described. Hehad short stature (-2.3 SD), diffuse goiter and a particularly large nodule in the right lobe of the thyroid gland. The endocrinological studies revealed slight hypothyroidism. He underwent surgical removal ofthe tumor, diagnosed histopathologically as follicular adenoma, embryonal type; and the diffuse goiter was diagnosed as dyshormonogenetic goiter. It was speculated that long-term hypersecretion of thyroid stimulating hormone (TSH) caused adenoma in the thyroid gland. Although the goiter disappeared after oral thyroxine replacement therapy, his height gain remained poor. Then, he was diagnosed partial growth hormone deficiency, and growth hormone therapy improved his height gain. It has been reported that a high percentage of patients with congenital hypothyroidism have additional anomalies. This is, however, the first reported case of dyshormonogenetic goiter complicated with growth hormonedeficiency.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 04:23:17