Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE PHOTOPHYSICS OF BETA-HOMO-TYROSINE AND ITS SIMPLE DERIVATIVES
Autore:
WICZK W; LANKIEWICZ L; CZAPLEWSKI C; ODZIEJ S; STACHOWIAK K; MICHNIEWICZ A; LIWO A;
Indirizzi:
UNIV GDANSK,FAC CHEM,SOBIESKIEGO 18 PL-80952 GDANSK POLAND
Titolo Testata:
Journal of photochemistry and photobiology. A, Chemistry
fascicolo: 2-3, volume: 101, anno: 1996,
pagine: 171 - 181
SICI:
1010-6030(1996)101:2-3<171:TPOBAI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
TIME-RESOLVED FLUORESCENCE; EXCITED-STATE; TRYPTOPHAN FLUORESCENCE; MOLECULAR-DYNAMICS; AMINO-ACIDS; DECAY; ANISOTROPY; CONFORMATIONS; KINETICS; RESIDUES;
Keywords:
BETA-HOMO-TYROSINE; PHOTOPHYSICS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
51
Recensione:
Indirizzi per estratti:
Citazione:
W. Wiczk et al., "THE PHOTOPHYSICS OF BETA-HOMO-TYROSINE AND ITS SIMPLE DERIVATIVES", Journal of photochemistry and photobiology. A, Chemistry, 101(2-3), 1996, pp. 171-181

Abstract

The synthetic derivatives of beta-homo-tyrosine (beta Hty), an analogue of tyrosine with an extra -CH2- incorporated between the carboxylicgroup and the CH carbon, modified at the amino group (free or acetylated), carboxyl group (free or amidated) and/or phenolic oxygen (free or methylated), were the subject of fluorescence studies and theoretical calculations in order to establish whether the rotamer model can be used to explain the fluorescence quenching of tyrosine. The N-acetylated derivatives of beta Hty with ionized carboxylate display biexponential fluorescence decay, whereas the other compounds show monoexponential fluorescence decay. Biexponential decay is assumed to be a result of the presence of low-energy conformers with a sufficiently high energy barrier to make them stable within the fluorescence timescale. The presence of stable conformers has been demonstrated by molecular mechanics and dynamics calculations. Moreover, in the case of beta Hty derivatives, the fluorescence quenching ability of the amide group depends on the distance between the chromophore, protonated amino and amide groups.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:04:33