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Titolo:
THERAPEUTIC RESULTS IN PATIENTS WITH SOFT -TISSUE SARCOMA - A RETROSPECTIVE STUDY TO IDENTIFY INDEPENDENT PROGNOSTIC VARIABLES
Autore:
FISCHER A; LUDEMANN M; SCHULTEMONTING J; FINKE J; IMDAHL A; FARTHMANN EH;
Indirizzi:
UNIV FREIBURG,CHIRURG KLIN,ABT ALLGEMEINE CHIRURG,HUGSTETTER STR 55 D-79106 FREIBURG GERMANY UNIV FREIBURG,CHIRURG KLIN,ABT ALLGEMEINE CHIRURG D-79106 FREIBURG GERMANY
Titolo Testata:
Zentralblatt fur Chirurgie
fascicolo: 10, volume: 122, anno: 1997,
pagine: 901 - 908
SICI:
0044-409X(1997)122:10<901:TRIPWS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
GER
Soggetto:
LOCAL RECURRENCE; RADIATION-THERAPY; RETROPERITONEAL SARCOMAS; MULTIMODALITY THERAPY; ADJUVANT CHEMOTHERAPY; CONSERVATIVE SURGERY; SURGICAL-TREATMENT; SURVIVAL; MANAGEMENT; EXTREMITY;
Keywords:
SOFT TISSUE SARCOMA; PROGNOSTIC FACTORS; COX MODEL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
A. Fischer et al., "THERAPEUTIC RESULTS IN PATIENTS WITH SOFT -TISSUE SARCOMA - A RETROSPECTIVE STUDY TO IDENTIFY INDEPENDENT PROGNOSTIC VARIABLES", Zentralblatt fur Chirurgie, 122(10), 1997, pp. 901-908

Abstract

The postoperative outcome of 108 patients with soft tissue sarcoma (STS) of the extremities, the retroperitoneum, or the trunk was investigated retrospectively to identify independent factors for the over all survival and local tumor control. Chi-square single factor analysis and a Cox model were used to identify independent postoperative risk factors. Single factor analysis revealed a significant correlation with negative effect on overall survival for the variables metastasis (p < 0,0001), chemotherapy (p < 0,0009), surgical procedures (0,001), tumor size >10 cm (p < 0,003), localization (retroperitoneum, trunk) (p < 0,03), and grading (G3/G4) (p < 0,03). Local tumor control was significantly correlated with the variable tumor size > 10 cm (p < 0,01). The Cox model showed a significant negative impact on overall survival for the factors metastasis (p < 0,002), tumor size > 10 cm (p < 0,004), grading (G3/G4) (p < 0,005), and sex (male) (p < 0,008). For local tumorcontrol the variables were age (p < 0,006), and surgical procedures (p < 0,01).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 10:22:52