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Titolo:
DISTRIBUTION AND LOCALIZATION OF A NOVEL CHOLECYSTOKININ-RELEASING FACTOR IN THE RAT GASTROINTESTINAL-TRACT
Autore:
TARASOVA N; SPANNAGEL AW; GREEN GM; GOMEZ G; REED JT; THOMPSON JC; HELLMICH MR; REEVE JR; LIDDLE RA; GREELEY GH;
Indirizzi:
UNIV TEXAS,MED BRANCH,DEPT SURG GALVESTON TX 77555 UNIV TEXAS,MED BRANCH,DEPT SURG GALVESTON TX 77555 NCI,FREDERICK CANC RES & DEV CTR,ABL BASIC RES PROGRAM FREDERICK MD 21702 UNIV TEXAS,HLTH SCI CTR,DEPT PHYSIOL SAN ANTONIO TX 78284 VET ADM W LOS ANGELES,CTR ULCER RES & EDUC LOS ANGELES CA 90073 VET ADM W LOS ANGELES,DIGEST DIS RES CTR LOS ANGELES CA 90073 DUKE UNIV,MED CTR,DEPT MED DURHAM NC 27710
Titolo Testata:
Endocrinology
fascicolo: 12, volume: 138, anno: 1997,
pagine: 5550 - 5554
SICI:
0013-7227(1997)138:12<5550:DALOAN>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PANCREATIC-ENZYME SECRETION; TRYPSIN-INHIBITOR; FEEDBACK-REGULATION; PEPTIDE; PLASMA; RADIOIMMUNOASSAY; PURIFICATION; SUPPRESSION; JUICE; GUT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
N. Tarasova et al., "DISTRIBUTION AND LOCALIZATION OF A NOVEL CHOLECYSTOKININ-RELEASING FACTOR IN THE RAT GASTROINTESTINAL-TRACT", Endocrinology, 138(12), 1997, pp. 5550-5554

Abstract

The purpose of this study was to examine the distribution and localization of an intestinal cholecystokinin (CCK)-releasing factor, called luminal CCK-releasing factor (LCRF), in the gastrointestinal tract andpancreas of the rat. RIA analysis indicates that LCRF immunoreactivity is found throughout the gut including the pancreas, stomach, duodenum, jejunum, ileum, and colon with the highest levels in the small intestine. Immunohistochemistry analysis shows LCRF immunoreactivity Staining in intestinal villi, Brunner's glands of the duodenum, the duodenal myenteric plexus, gastric pits, pancreatic ductules, and pancreatic islets. These results indicate potential sources for secretagogue-stimulated release of luminal LCRF and support the hypothesis that LCRF issecreted into the intestinal lumen to stimulate CCK release from mucosal CCK cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 00:21:23