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Titolo:
ENHANCING NERVE REGENERATION ACROSS A SILICONE TUBE CONDUIT BY USING INTERPOSED SHORT-SEGMENT NERVE GRAFTS
Autore:
FRANCEL PC; FRANCEL TJ; MACKINNON SE; HERTL C;
Indirizzi:
WASHINGTON UNIV,DIV PLAST SURG,1 BARNES HOSP PLAZA,SUITE 17424 ST LOUIS MO 63110 WASHINGTON UNIV,DIV PLAST SURG ST LOUIS MO 63110 WASHINGTON UNIV,DEPT SURG ST LOUIS MO 63110 UNIV OKLAHOMA,HLTH SCI CTR,DEPT NEUROL SURG,PRESBYTERIAN NEUROL INST OKLAHOMA CITY OK 00000
Titolo Testata:
Journal of neurosurgery
fascicolo: 6, volume: 87, anno: 1997,
pagine: 887 - 892
SICI:
0022-3085(1997)87:6<887:ENRAAS>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUTOGENOUS VEIN GRAFT; RAT SCIATIC-NERVE; PERIPHERAL-NERVE; ACCUMULATING INVIVO; REPAIR; CHAMBERS; MUSCLE; GAP; GUIDANCE; GROWTH;
Keywords:
NERVE REGENERATION; SILICONE TUBE; INTERPOSED NERVE GRAFT; HISTOLOGICAL, ELECTROPHYSIOLOGICAL, AND FUNCTIONAL RESULTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
53
Recensione:
Indirizzi per estratti:
Citazione:
P.C. Francel et al., "ENHANCING NERVE REGENERATION ACROSS A SILICONE TUBE CONDUIT BY USING INTERPOSED SHORT-SEGMENT NERVE GRAFTS", Journal of neurosurgery, 87(6), 1997, pp. 887-892

Abstract

Isolated nerve segments may inherently contain all of the necessary factors required to support regeneration within a silicone tube conduitplaced across a nerve gap. Thirty-six adult Lewis rats each weighing approximately 250 g were randomized into three groups. A sciatic nervegap (13-15 mm in length) was bridged by an empty silicone tube (GroupI), a silicone tube containing a short 2-mm interposed nerve segment (Group II), or a nerve autograft (Group III). At 16 weeks postoperatively, no regeneration was observed through the empty silicone tube. In contrast, regeneration across the silicone tube containing the isolated nerve segment was equivalent to that noted through nerve autografts as assessed by histological, electrophysiological, and functional criteria. Thus, an interposed nerve segment will extend the length of successful nerve regeneration through a silicone tube conduit.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 20:11:02