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Titolo:
LANGUAGE AND COMMUNICATION IN FRAGILE-X-SYNDROME
Autore:
ABBEDUTO L; HAGERMAN RJ;
Indirizzi:
UNIV WISCONSIN,WAISMAN CTR MENTAL RETARDAT & HUMAN DEV,1500 HIGHLAND AVE MADISON WI 53705 UNIV WISCONSIN,DEPT EDUC PSYCHOL MADISON WI 53705 UNIV COLORADO,HLTH SCI CTR,DEPT PEDIAT DENVER CO 80262 CHILDRENS HOSP,CHILD DEV UNIT DENVER CO 80218
Titolo Testata:
Mental retardation and developmental disabilities research reviews
fascicolo: 4, volume: 3, anno: 1997,
pagine: 313 - 322
SICI:
1080-4013(1997)3:4<313:LACIF>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MENTAL-RETARDATION; ADAPTIVE-BEHAVIOR; SAMPLING CONTEXT; FULL MUTATION; MALES; AUTISM; GENE; CHILDREN; FMR-1; PHENOTYPE;
Keywords:
FRAGILE X SYNDROME; SPEECH; LANGUAGE; COMMUNICATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
92
Recensione:
Indirizzi per estratti:
Citazione:
L. Abbeduto e R.J. Hagerman, "LANGUAGE AND COMMUNICATION IN FRAGILE-X-SYNDROME", Mental retardation and developmental disabilities research reviews, 3(4), 1997, pp. 313-322

Abstract

In this article, we describe the language and communication problems of individuals with fragile X syndrome (FXS). FXS is a common genetic disorder resulting from a single-gene mutation on the X chromosome. Itis associated with a wide spectrum of physical, behavioral, cognitive, and language problems. Males are typically more severely affected than females, with the vast majority of males having mental retardation. Language and communication are negatively affected by problems in oral-motor structure and function and by conductive hearing loss associated with recurrent otitis media. Speech problems of males with FXS include variability in rate and stuttering-like repetition of sounds. The pattern of speech problems displayed by males is unique to FXS and mayreflect a form of developmental dyspraxia. Lexical development is serious delayed in males with FXS. It is less clear, however, whether lexical development keeps pace with achievements in cognitive developmentand whether receptive and expressive vocabularies are equally impaired. Morphosyntactic development is delayed in males with FXS, with receptive morphosyntax being mental-age-appropriate. It is less clear whether expressive morphosyntactic keeps pace with mental age in affected males. Communication problems are characteristic of both males and females and include features that are syndrome-specific. Most notable among the features displayed by males with FXS is perseveration on a word, phrase, or topic in conversation. Several hypotheses have been advanced to explain this perseveration, but the most promising focus is on hyperarousal and frontal-lobe-executive function deficits. Females with FXS display a run-on, disorganized, and tangential style of conversation that may result from their well-documented frontal-lobe-executivefunction deficits. Language and communication intervention for affected individuals requires coordination of medical and behavioral approaches, with the involvement of professionals from several disciplines. Future research must focus on females, on language problems suggested by clinical experience, and on connections between language and communication problems and problems at the neurological and molecular geneticlevels. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 16:28:15