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Titolo:
SIMULTANEOUS DOBUTAMINE STRESS ECHOCARDIOGRAPHY AND TL-201 PERFUSION IMAGING FOR THE DETECTION OF CORONARY-ARTERY DISEASE
Autore:
HUANG PJ; HO YL; WU CC; CHAO CL; CHEN MF; CHENG PU; LEE YT;
Indirizzi:
NATL TAIWAN UNIV HOSP,DEPT INTERNAL MED,DIV CARDIOL,7 CHUNG SHAN S RDTAIPEI 10016 TAIWAN NATL TAIWAN UNIV HOSP,DEPT RADIOL TAIPEI 10016 TAIWAN
Titolo Testata:
Cardiology
fascicolo: 6, volume: 88, anno: 1997,
pagine: 556 - 562
SICI:
0008-6312(1997)88:6<556:SDSEAT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; TL-201 TOMOGRAPHY; FREQUENT SOURCE; SCINTIGRAPHY; INFUSION; EXERCISE; DEFECTS; ABILITY; HEART; SPECT;
Keywords:
DOBUTAMINE STRESS ECHOCARDIOGRAPHY; CORONARY ARTERY DISEASE; DOBUTAMINE TL-201 SCINTIGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
P.J. Huang et al., "SIMULTANEOUS DOBUTAMINE STRESS ECHOCARDIOGRAPHY AND TL-201 PERFUSION IMAGING FOR THE DETECTION OF CORONARY-ARTERY DISEASE", Cardiology, 88(6), 1997, pp. 556-562

Abstract

To compare the diagnostic value of dobutamine stress echocardiographywith dobutamine thallium-201 single-photon-emission computed tomography (SPECT) in detecting coronary artery disease, we performed both tests simultaneously on 93 patients who also underwent coronary arteriography. Dobutamine was infused at rates of 5, 10, 20, 30 and 40 mu g/kg/min in 3-min stages, The left ventricle was divided into anteroseptal,posterolateral and inferior regions. Within each region, wall motion or perfusion abnormalities were classified as normal, ischemia or fixed defect. The response to stress was concordantly classified by both tests in 67 patients (72%, kappa = 0.48). Regional agreement for abnormalities was observed in 79% (kappa = 0.56) of the 279 regions analyzed. Dobutamine echocardiography detected 62 (93%) and thallium SPECT 60 (90%, p = NS) of the 67 patients with significant corollary artery disease (greater than or equal to 50% diameter stenosis). The specificitywas 77 (20 of 26) and 81% (21 of 26), respectively. The accuracy was 88 and 87%, respectively. Combined the two tests gave a sensitivity of97% a specificity of 65% and an accuracy of 88%. The accuracy for detecting individual coronary stenosis with echocardiography was 83% for the left anterior descending artery, 84% for the right coronary arteryand 73% for the left circumflex artery. With SPECT, it was 83, 87 and76%, respectively. In conclusion, dobutamine stress echocardiography and thallium SPECT provide a comparable accuracy for detection and localization of coronary artery disease, and for identification of regional myocardial abnormalities. Performing the two tests simultaneously is feasible but it adds limited value in detecting coronary artery disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:09:18