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Titolo:
A CASE-CONTROL STUDY ON RISK-FACTORS FOR LOCAL RECURRENCES OR DISTANTMETASTASES IN BREAST-CANCER PATIENTS TREATED WITH BREAST-CONSERVING SURGERY
Autore:
NOGUCHI S; KOYAMA H; KASUGAI T; TSUKUMA H; TSUJI N; TSUDA H; AKIYAMA F; MOTOMURA K; INAJI H;
Indirizzi:
OSAKA MED CTR CANC & CARDIOVASC DIS,DEPT SURG,HIGASHINARI KU,1-3-3 NAKAMICHI OSAKA 537 JAPAN OSAKA MED CTR CANC & CARDIOVASC DIS,DEPT PATHOL,HIGASHINARI KU OSAKA 537 JAPAN OSAKA MED CTR CANC & CARDIOVASC DIS,DEPT FIELD RES,HIGASHINARI KU OSAKA 537 JAPAN NATL CANC CTR,DEPT PATHOL TOKYO JAPAN CANC INST HOSP,DEPT PATHOL TOKYO JAPAN
Titolo Testata:
Oncology
fascicolo: 6, volume: 54, anno: 1997,
pagine: 468 - 474
SICI:
0030-2414(1997)54:6<468:ACSORF>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPARING TOTAL MASTECTOMY; TUMOR-SUPPRESSOR GENE; CONSERVATION THERAPY; TRIAL; PREMENOPAUSAL; IRRADIATION; LUMPECTOMY; CARCINOMA;
Keywords:
BREAST-CONSERVING SURGERY; RECURRENCES LOCAL; METASTASES DISTANT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
S. Noguchi et al., "A CASE-CONTROL STUDY ON RISK-FACTORS FOR LOCAL RECURRENCES OR DISTANTMETASTASES IN BREAST-CANCER PATIENTS TREATED WITH BREAST-CONSERVING SURGERY", Oncology, 54(6), 1997, pp. 468-474

Abstract

A case-control study was conducted on 143 case-control sets recruitedfrom the 18 key hospitals/institutes in Japan to identify risk factors for local recurrences and distant metastases after breast-conservingsurgery in breast cancer patients: (1) positive surgical margin was arisk factor for local recurrences (relative risk (RR) = 16.70, p < 0.001) but not for distant metastases, (?) positive p53 immunostaining was a risk factor for both local recurrences (RR = 5.62, p = 0.003) anddistant metastases (RR = 3.11, p = 0.034), (3) lymph node metastasis was a risk factor for distant metastases (RR = 9.28, p = 0.001) but not for local recurrences, (4) radiation therapy reduced local recurrences (RR = 0.13, p = 0.004) and (5) adjuvant chemotherapy (RR = 0.27, p = 0.120), endocrine therapy (RR = 0.21, p = 0.037), and chemoendocrinetherapy (RR = 0.05, p = 0.013) reduced local recurrences.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 11:42:48