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Titolo:
MOTION PERCEPTION AND ALZHEIMERS-DISEASE
Autore:
GILMORE GC; WENK HE; NAYLOR LA; KOSS E;
Indirizzi:
CASE WESTERN RESERVE UNIV,DEPT PSYCHOL,10900 EUCLID AVE CLEVELAND OH 44106
Titolo Testata:
Journal of gerontology
fascicolo: 2, volume: 49, anno: 1994,
pagine: 52 - 57
SICI:
0022-1422(1994)49:2<52:MPAA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
VISUAL AREA MT; CONTRAST SENSITIVITY; MACAQUE MONKEY; CORTEX; RESPONSES; DEFICITS; MOVEMENT; NEURONS; LESIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
G.C. Gilmore et al., "MOTION PERCEPTION AND ALZHEIMERS-DISEASE", Journal of gerontology, 49(2), 1994, pp. 52-57

Abstract

The motion sensitivity of 15 probable Alzheimer disease (AD) patientsand 15 healthy elderly adults was investigated with a correlated motion paradigm. The AD patients exhibited significantly higher thresholdsfor detecting file direction of motion. Contrast sensitivity for a 2 cpd, 7.5 Hz counterphased stimulus was related to motion threshold in the AD group. There also was a significant relationship between an index of dementia severity, Mini-Mental State Exam (MMSE), and motion sensitivity. The results support tire hypothesis proposed from neuroanatomical evidence by Hof and Morrison (1990) that AD results in a disruption of the visual signals mediated by area 17. Further, the data suggest that this disruption of visual processing is linked to the progression of dementia. The study offers support for the hypothesis that AD leads to a deficit in the magnocellular or M pathway of visual processing.

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Documento generato il 27/09/20 alle ore 22:54:16