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Titolo:
STRESS-LIKE ADRENOCORTICOTROPIN RESPONSES TO CAFFEINE IN YOUNG HEALTHY-MEN
Autore:
LOVALLO WR; ALABSI M; BLICK K; WHITSETT TL; WILSON MF;
Indirizzi:
UNIV OKLAHOMA,HLTH SCI CTR,VET AFFAIRS MED CTR 151A,921 NE 13TH ST OKLAHOMA CITY OK 73190 UNIV OKLAHOMA,HLTH SCI CTR,DEPT PSYCHIAT & BEHAV SCI OKLAHOMA CITY OK73190 UNIV OKLAHOMA,HLTH SCI CTR,DEPT PATHOL OKLAHOMA CITY OK 00000 UNIV OKLAHOMA,HLTH SCI CTR,DEPT MED OKLAHOMA CITY OK 00000
Titolo Testata:
Pharmacology, biochemistry and behavior
fascicolo: 3, volume: 55, anno: 1996,
pagine: 365 - 369
SICI:
0091-3057(1996)55:3<365:SARTCI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE REACTIVITY; NEUROENDOCRINE RESPONSES; BLOOD-PRESSURE; ENDOCRINE; CORTISOL;
Keywords:
ACTH; CORTISOL; CAFFEINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
W.R. Lovallo et al., "STRESS-LIKE ADRENOCORTICOTROPIN RESPONSES TO CAFFEINE IN YOUNG HEALTHY-MEN", Pharmacology, biochemistry and behavior, 55(3), 1996, pp. 365-369

Abstract

The effects of oral caffeine (3.3 mg/kg, equivalent to 2-3 cups of coffee) on plasma adrenocorticotropin (ACTH) and cortisol (CORT) were tested in 47 healthy young men at rest in a double-blind, placebo-controlled, crossover study. Following caffeine, ACTH was significantly elevated at all times from 30 min to 180 min, and CORT was elevated from 60 min to 120 min (Fs greater than or equal to 8.4, ps<0.01). Peak increases relative to placebo were: ACTH, 33% (+5.2 pg/ml) and CORT, 30% (2.7 mu g/dl) at 60 min postcaffeine. The results suggest that caffeine can activate important components of the pituitary-adrenocortical response in humans during the resting state. Caffeine's known ability toincrease CORT production appears at least partly due to an increase in ACTH release at the pituitary. Copyright (C) 1996 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/10/20 alle ore 11:56:16