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Titolo:
IMMUNOLOGICAL BEHAVIOR OF THE MENINGOCOCC AL VACCINES
Autore:
REQUEJO HIZ;
Indirizzi:
AV DR ARNALDO 355 BR-01246902 SAO PAULO BRAZIL INST ADOLFO LUTZ REGISTRO,SECAO IMUNOL SAO PAULO BRAZIL
Titolo Testata:
Revista de Saude Publica
fascicolo: 4, volume: 31, anno: 1997,
pagine: 402 - 416
SICI:
0034-8910(1997)31:4<402:IBOTMA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
POR
Soggetto:
CAPSULAR POLYSACCHARIDE VACCINE; NEISSERIA-MENINGITIDIS GROUP; MEMBRANE VESICLE VACCINE; SEROGROUP-B MENINGOCOCCI; GROUP-C POLYSACCHARIDE; HUMAN IMMUNE-RESPONSE; ESCHERICHIA-COLI K1; GROUP-A; CONJUGATE VACCINE; ANTIBODY-RESPONSE;
Keywords:
BACTERIAL VACCINES; MENINGITIS, MENINGOCOCCAL, IMMUNOLOGY; IMMUNITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
100
Recensione:
Indirizzi per estratti:
Citazione:
H.I.Z. Requejo, "IMMUNOLOGICAL BEHAVIOR OF THE MENINGOCOCC AL VACCINES", Revista de Saude Publica, 31(4), 1997, pp. 402-416

Abstract

Meningococcal disease continues to be a great health problem on all continents and rite meningococcal vaccines have been proposed for theirprevention and epidermic control. The polysaccharide A and C vaccinesare relatively efficacious with distinct distinct immunological behavior with regard to the different age groups, however, up to the present no highly efficacious vaccine for meningococcal B disease exists. The meningococcal B capsular polysaccharide is not immunogenic due to the structural mimicry of mammalian tissues and efforts to produce carrier proteins have been proposed in order to obtain an immunogenic vaccine for all age groups that would if possible, protect against all the meningococci. This review of the literature presents the study of the development of the immunological behavior of all the meningococcal vaccines undergoing development and reports of the efforts to obtain a safe and efficacious product for the control of meningococcal disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:34:49