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Titolo:
PULMONARY AND EXTRAPULMONARY TUBERCULOSIS AT AIDS DIAGNOSIS IN SPAIN - EPIDEMIOLOGIC DIFFERENCES AND IMPLICATIONS FOR CONTROL
Autore:
CASTILLA J; GUTIERREZ A; GUERRA L; DELAPAZ JP; NOGUER I; RUIZ C; BELZA MJ; CANON J;
Indirizzi:
CARLOS III INST PUBL HLTH,CTR NACL EPIDEMIOL,SINESIO DELGADO 6 MADRID28029 SPAIN SECRETARIAT NATL AIDS PLAN MADRID SPAIN
Titolo Testata:
AIDS
fascicolo: 13, volume: 11, anno: 1997,
pagine: 1583 - 1588
SICI:
0269-9370(1997)11:13<1583:PAETAA>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS-INFECTION; NEW-YORK-CITY; DEFINING DISEASE; HIV-INFECTION; UNITED-STATES; TRANSMISSION; EPIDEMIC; RISK;
Keywords:
TUBERCULOSIS; AIDS; SPAIN; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
J. Castilla et al., "PULMONARY AND EXTRAPULMONARY TUBERCULOSIS AT AIDS DIAGNOSIS IN SPAIN - EPIDEMIOLOGIC DIFFERENCES AND IMPLICATIONS FOR CONTROL", AIDS, 11(13), 1997, pp. 1583-1588

Abstract

Objective: To ascertain the differential Factors associated with pulmonary versus extrapulmonary tuberculosis (TB) at AIDS diagnosis in Spain. Design: Analysis of AIDS surveillance data. Methods: Data about AIDS patients, aged 12 years and over, diagnosed in 1995 were taken fromthe Spanish AIDS Register. The respective proportions of cases presenting with pulmonary and extrapulmonary TB at AIDS diagnosis were analysed by gender, age, HIV transmission category, prison record, province, country of origin and CD4+ lymphocyte count. A multivariate analysiswas carried out using logistic regression analysis. Results: Of 6161 AIDS cases analysed, 20.1% presented with pulmonary TB and 20.4% with extrapulmonary TB. Overall, TB showed association with men, age under 30 years, injecting drug users (IDU), cases of heterosexual HIV transmission, and concurrent or past stay in prison. Frequency of TB proved no different among foreign-born patients. Pulmonary and extrapulmonaryTB showed a similar distribution for most of the variables. Current prison inmates registered a high risk of pulmonary TB [adjusted odds ratio (OR), 4.2; 99% confidence interval (CI), 3.1-5.8] compared with patients without prison record, and ex-prison inmates registered an intermediate risk (OR, 2.3; 99% CI, 1.8-3.0). Among patients with TB at AIDS diagnosis, pulmonary TB was associated with subjects currently in prison (OR, 2.1; 99% CI, 1.5-3.0) and injecting drug use (OR, 1.5; 99% CI, 1.0-2.4). Pulmonary TB presented with higher CD4+ lymphocyte counts than extrapulmonary TB (P < 0.001). Conclusions: The results suggestthe importance that recent transmission of Te may be having among young adults, IDU and prison inmates in particular, and calls for a review of control strategies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/08/20 alle ore 19:43:14