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Titolo:
EARLY VERSUS LATE CORONARY STENTING FOLLOWING ACUTE MYOCARDIAL-INFARCTION - RESULTS OF THE STENTIM-I STUDY (FRENCH REGISTRY OF STENTING IN ACUTE MYOCARDIAL-INFARCTION)
Autore:
MONASSIER JP; HAMON M; ELIAS J; MAILLARD L; SPAULDING C; RAYNAUD P; CRIBIER A; BARRAGAN P; JULIARD JM; LEFEVRE T; AUBRY P; FAUGIER JP; MASQUET C; RIOUX P; BEDOSSA M; JOLY P; PETITEAU PY; ROYER T; MORICE MC; RORIZ R; CATTAN S; MEYER P; BLANCHARD D; KHALIFE K;
Indirizzi:
HOP EMILE MULLER,UNITE PATHOL CORONAIRE & CARDIOL INTERVENT F-68070 MULHOUSE FRANCE HOP EMILE MULLER,UNITE PATHOL CORONAIRE & CARDIOL INTERVENT F-68070 MULHOUSE FRANCE
Titolo Testata:
Catheterization and cardiovascular diagnosis
fascicolo: 3, volume: 42, anno: 1997,
pagine: 243 - 248
SICI:
0098-6569(1997)42:3<243:EVLCSF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMEDIATE ANGIOPLASTY; ANTIPLATELET THERAPY; BALLOON ANGIOPLASTY; ARTERY DISEASE; IMPLANTATION; TICLOPIDINE; PLACEMENT; ANTICOAGULATION; MULTICENTER; ULTRASOUND;
Keywords:
STENT; CORONARY ANGIOPLASTY; ACUTE MYOCARDIAL INFARCTION; TICLOPIDIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Monassier et al., "EARLY VERSUS LATE CORONARY STENTING FOLLOWING ACUTE MYOCARDIAL-INFARCTION - RESULTS OF THE STENTIM-I STUDY (FRENCH REGISTRY OF STENTING IN ACUTE MYOCARDIAL-INFARCTION)", Catheterization and cardiovascular diagnosis, 42(3), 1997, pp. 243-248

Abstract

This study was undertaken to determine the feasibility and safety of coronary stenting in acute myocardial infarction (AMI). In AMI, primary percutaneous transluminal coronary angioplasty (PTCA) is accepted asthe preferred method of reperfusion for patients presenting at highlyexperienced centres. Until recently, however, stenting has been avoided during AMI because of a potential high risk of thrombosis. This prospective observational study carried out in 20 centres and included 648 consecutive patients who underwent PTCA with stent implantation for AMI. Of these 648 patients, 269 (41.5%, Group 1) were dilated early (<24 hr) after the onset of the symptoms (75% treated by direct PTCA) and 379 (58.5%, Group 2) were dilated between 24 hr and 14 days after AMI. Combined therapy with ticlopidin and aspirin was used after the procedure. Bailout stenting occurred more often in Group 1 than in Group 2 (17% vs. 9.5%) (P < 0.05). Angiographic successful stenting was similar in both groups of patients (96% vs. 97%). During the hospital follow-up period, stent thrombosis occurred in eight patients (3%) in Group 1 and in six patients (1.6%) in Group 2 (NS). There was 14 deaths (5.2%) in Group 1 and 11 deaths (3.9%) in Group 2 (NS). After multivariate analysis bailout stenting was identified as the sole predictor of stent thrombosis (P < 0.0001). Vascular access-site complications occurred in six patients (1%) with no difference between the two groups. This study indicates that patients who receive a coronary stent in AMI can be managed safely with antiplatelet therapy. Randomized studies areneeded to determine the precise indication for coronary stenting as an adjunct to primary PTCA. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:49:24