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Titolo:
INDUCTION OF ST-SEGMENT ELEVATION BY REGIONAL MYOCARDIAL STRETCH IN NORMAL CANINE HEARTS IN-VIVO
Autore:
SHIMADA M; NAKAMURA Y; ASAKURA K; IWANAGA S; HATTORI S; TAKAHASHI M; OGAWA S;
Indirizzi:
KITASATO INST HOSP,DEPT INTERNAL MED,MINATO KU,5-9-1 SHIROGANE TOKYO 108 JAPAN KEIO UNIV,SCH MED,DEPT INTERNAL MED,CARDIOPULM DIV TOKYO JAPAN
Titolo Testata:
Japanese Circulation Journal
fascicolo: 11, volume: 61, anno: 1997,
pagine: 921 - 926
SICI:
0047-1828(1997)61:11<921:IOSEBR>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
POTASSIUM CHANNELS; ION CHANNELS; ISCHEMIA;
Keywords:
REGIONAL MYOCARDIAL STRETCH; STRAIN GAUGE ARCH; ST-SEGMENT ELEVATION; SYSTOLIC BULGING; MECHANOELECTRICAL FEEDBACK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
M. Shimada et al., "INDUCTION OF ST-SEGMENT ELEVATION BY REGIONAL MYOCARDIAL STRETCH IN NORMAL CANINE HEARTS IN-VIVO", Japanese Circulation Journal, 61(11), 1997, pp. 921-926

Abstract

The purpose of this study was to evaluate ST-segment elevation induced by regional myocardial stretch without myocardial ischemia in caninehearts. A strain gauge arch (TH-601T) was sutured to the left ventricular epicardium, parallel to the short axis, to shorten the end-diastolic length of the myocardium beneath the arch (stretch zone; SZ) and to produce regional myocardial stretch in each of 6 dogs. An increase in preload caused by altering the height of a saline-filled reservoir affected prolongation or shortening of the myocardium both in the SZ and outside the arch (normal zone; NZ) to increase myocardial stretch. An epicardial electrocardiogam was recorded in both the SZ and the NZ. After suture of the strain gauge arch, the ST segment was elevated in the SZ. An increase in preload augmented stretch during systole in theSZ, resulting in additional ST-segment elevation. These results suggest that regional myocardial stretch itself plays an important role in ST-segment elevation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 21:37:19