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Titolo:
NONARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY - TIME OF ONSET OF VISUAL-LOSS
Autore:
HAYREH SS; PODHAJSKY PA; ZIMMERMAN B;
Indirizzi:
UNIV IOWA HOSP & CLIN,DEPT OPHTHALMOL,200 HAWKINS DR IOWA CITY IA 52242 UNIV IOWA,COLL MED,DEPT OPHTHALMOL IOWA CITY IA 52242 UNIV IOWA,COLL MED,DEPT PREVENT MED & ENVIRONM HLTH,DIV BIOSTAT IOWA CITY IA 52242
Titolo Testata:
American journal of ophthalmology
fascicolo: 5, volume: 124, anno: 1997,
pagine: 641 - 647
SICI:
0002-9394(1997)124:5<641:NAION->2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEASONAL-VARIATION; BLOOD-PRESSURE; NERVE HEAD; PLATELET; SUBENDOTHELIUM; PATHOGENESIS; TEMPERATURE; MORTALITY; CORONARY; SIZE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
S.S. Hayreh et al., "NONARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY - TIME OF ONSET OF VISUAL-LOSS", American journal of ophthalmology, 124(5), 1997, pp. 641-647

Abstract

PURPOSE: To study time of day and seasonal variation of onset of: visual loss in nonarteritic anterior ischemic optic neuropathy (AION). METHODS: From 1975 to 1995, we prospectively investigated the time of discovery of visual loss in 635 patients (871 eyes) with AION-a total of925 episodes. Data were analyzed for two variables: time of day of discovery of visual loss for 544 episodes and seasonal variation of the onset of AION for 839 episodes. RESULTS: Of 544 episodes, time of day for discovery of visual loss was upon awakening from sleep in the morning or a nap in 282 (51.8%), during the first opportunity to use vision critically early in the morning in 117 (21.5%), and later in the dayin 145 (26.7%). AION was significantly (P = .0030) more frequent in summer than winter. Estimated monthly onset rates were 82.7 episodes (95% confidence interval [CI], 71.3 to 95.8) in summer, 58.3 (95% CI, 48.9 to 69.6) in winter, 66.0 (95% CI, 55.9 to 71.9) in spring, and 72.7(95% CI, 62.1 to 85.1) in fall. Onset significantly (P < .0001) occurred more during hot than cold months, with the estimated monthly rate of onset in hot months of 82.2 episodes (95% CT, 73.7 to 91.8) compared with 59.8 (95% CI, 53.3 to 67.1) in cold months. CONCLUSIONS: Tn at least 399 (73.3%) of 544 episodes of AION, patients discovered visual loss upon first awakening or at first. opportunity to use vision critically after sleeping, suggesting that nocturnal arterial hypotension may play an important role, Also, AION developed more often in summer than in winter.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 09:46:48