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Titolo:
AKINETIC MUTISM - DISCONNECTION OF FRONTAL-SUBCORTICAL CIRCUITS
Autore:
MEGA MS; COHENOUR RC;
Indirizzi:
UNIV CALIF LOS ANGELES,SCH MED,LAB NEURO IMAGING,DEPT NEUROL,710 WESTWOOD PLAZA LOS ANGELES CA 90095
Titolo Testata:
Neuropsychiatry, neuropsychology, and behavioral neurology
fascicolo: 4, volume: 10, anno: 1997,
pagine: 254 - 259
SICI:
0894-878X(1997)10:4<254:AM-DOF>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBON-MONOXIDE INTOXICATION; BILATERAL PALLIDAL LESIONS; BASAL GANGLIA; EFFERENT PROJECTIONS; RHESUS-MONKEY; APHASIA; ORGANIZATION; INFARCTION; NUCLEUS; DAMAGE;
Keywords:
NEUROBEHAVIOR; AKINETIC MUTISM; GLOBUS PALLIDUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
62
Recensione:
Indirizzi per estratti:
Citazione:
M.S. Mega e R.C. Cohenour, "AKINETIC MUTISM - DISCONNECTION OF FRONTAL-SUBCORTICAL CIRCUITS", Neuropsychiatry, neuropsychology, and behavioral neurology, 10(4), 1997, pp. 254-259

Abstract

Akinetic mutism may result from anterior cingulate lesions or a disconnection of the limbic connections projecting from the cingulate through subcortical circuits, Based on nonhuman primate tracer studies, ventral pallidal lesions should disrupt the anterior cingulate frontal-subcortical circuit. A patient developed a rigid akinetic mute stare caused by bilateral lesions of the globus pallidus interna with ventral extension. The anatomic basis of the patient's clinical findings support a similarity in frontal-subcortical anatomy between humans and nonhuman primates, Isolated pallidal lesions are rare. Future studies should document whether ventral extension below the anterior commissure is associated with a loss of motivation.

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Documento generato il 14/07/20 alle ore 19:18:23