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Titolo:
CHANGES IN BRAIN GENE-EXPRESSION IN PSYCHIATRIC-ILLNESS - MESSENGER-RNA DIFFERENTIAL DISPLAY PROVIDES SOME CLUES
Autore:
FLANIGAN TP; LESLIE RA;
Indirizzi:
UNIV OXFORD,SMITHKLINE BEECHAM CTR APPL NEUROPSYCOBIOL,RADCLIFFE INFIRM,DEPT CLIN PHARMACOL OXFORD OX2 6HE ENGLAND
Titolo Testata:
Molecular psychiatry
fascicolo: 6, volume: 2, anno: 1997,
pagine: 451 - 456
SICI:
1359-4184(1997)2:6<451:CIBGIP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA EXPRESSION; C-FOS PROTEIN; RAT-BRAIN; MOLECULAR-CLONING; COMPLEMENTARY-DNA; IDENTIFICATION; PCR; CELLS; STRIATUM; CANCER;
Keywords:
DEPRESSION; ANXIETY; SCHIZOPHRENIA; ADDICTION; NEUROPLASTICITY; NEUROADAPTATION; CENTRAL NERVOUS SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
53
Recensione:
Indirizzi per estratti:
Citazione:
T.P. Flanigan e R.A. Leslie, "CHANGES IN BRAIN GENE-EXPRESSION IN PSYCHIATRIC-ILLNESS - MESSENGER-RNA DIFFERENTIAL DISPLAY PROVIDES SOME CLUES", Molecular psychiatry, 2(6), 1997, pp. 451-456

Abstract

The 20th century has witnessed a progressive increase in our understanding of brain structure, organisation and function and now includes knowledge at the macromolecular and ionic levels. Investigations of such diverse functions as cognition, memory and mood, performed mainly inwhole animal studies, are now advancing rapidly with the application of modern molecular biological techniques. In this article we considerthe contribution of mRNA differential display to the analysis of altered gene expression in vitro and in vivo. The role that this techniquemay play in the identification of genes involved in the aetiology of psychiatric disorders and their treatment is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 09:44:56