Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
INTERSTITIAL LASER THERMOTHERAPY IN PIG-LIVER - EFFECT OF INFLOW OCCLUSION ON EXTENT OF NECROSIS AND ULTRASOUND IMAGE
Autore:
MOLLER PH; HANNESSON PH; IVARSSON K; OLSRUD J; STENRAM U; TRANBERG KG;
Indirizzi:
LUND UNIV,DEPT SURG S-22185 LUND SWEDEN LUND UNIV,DEPT RADIOL S-22185 LUND SWEDEN LUND UNIV,DEPT RADIAT PHYS S-22185 LUND SWEDEN LUND UNIV,DEPT PATHOL S-22185 LUND SWEDEN
Titolo Testata:
Hepato-gastroenterology
fascicolo: 17, volume: 44, anno: 1997,
pagine: 1302 - 1311
SICI:
0172-6390(1997)44:17<1302:ILTIP->2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ND-YAG LASER; HEPATIC METASTASES; CLINICAL USE; PHOTOCOAGULATION; HYPERTHERMIA; ABLATION; ISCHEMIA; LESIONS; TUMORS; TISSUE;
Keywords:
INTERSTITIAL THERAPY; THERMOTHERAPY; ND-YAG LASER; ULTRASONOGRAPHY; TEMPERATURE DISTRIBUTION; FEEDBACK CONTROL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
P.H. Moller et al., "INTERSTITIAL LASER THERMOTHERAPY IN PIG-LIVER - EFFECT OF INFLOW OCCLUSION ON EXTENT OF NECROSIS AND ULTRASOUND IMAGE", Hepato-gastroenterology, 44(17), 1997, pp. 1302-1311

Abstract

Background/Aims: The aim was to investigate the effect of blood inflow occlusion. on lesion. size and ultrasonographic findings during interstitial laser thermotherapy of normal liver. Methodology: Pigs were treated with or without hepatic inflow occlusion at a Laser power of 3Wor without inflow occlusion at 5 W (target temperature 43 degrees C). The thermotherapy system consisted of an Nd:YAG Laser and a temperature feedback circuit. Ultrasonography was performed immediately after treatment. Lesion size was determined using Light microscopy including immunohistochemistry with bromodeoxyuridine. Results: Hyperechoic ultrasonographic changes were observed after treatment with inflow occlusion or when there was carbonization. If carbonization did not occur, unoccluded blood flow was associated with hypoechoic lesions. Following inflow occlusion, maximum lesion width 2 and 6 days after thermotherapy averaged 21.9 +/- 1.3 and 20.2 +/- 0.8 (means +/- SEM) mm, respectively. This was larger than the corresponding values of 10.8 +/- 0.8 and11.1 +/- 2.0 observed after treatment without inflow occlusion at 3W (p<0.01). Increase in, laser power from 3 to 5W in experiments withoutinflow occlusion produced early carbonization. and a slight increase in. lesion size that did not match that produced by inflow occlusion. Ultrasound gave a correct prediction of necrosis size after treatment with inflow occlusion but overestimated the necrosis when inflow occlusion was not used. Ultrasound was furthermore unable to predict size of necrosis in individual experiments. Conclusion: Blood flow has a major influence on lesion size in interstitial laser thermotherapy of theliver and affects ultrasonographic images. Also, it appears that intraoperative ultrasonography cannot monitor lesion size with an accuracythat is sufficient for clinical use.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 20:58:51