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Titolo:
GENOTOXICITY STUDIES ON THE INSECTICIDE DURSBAN IN ROOT-MERISTEM CELLS OF CREPIS-CAPILLARIS L
Autore:
DIMITROV B; GADEVA P;
Indirizzi:
BULGARIAN ACAD SCI,INST GENET BU-1113 SOFIA BULGARIA
Titolo Testata:
Environmental and experimental botany
fascicolo: 2-3, volume: 37, anno: 1997,
pagine: 199 - 209
SICI:
0098-8472(1997)37:2-3<199:GSOTID>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOUSE BONE-MARROW; MICRONUCLEUS ASSAY; CHROMOSOMAL-ABERRATIONS; HUMAN-LYMPHOCYTES; VICIA-FABA; PESTICIDES; CLASTOGENS; SIZE; DNA;
Keywords:
DURSBAN; INSECTICIDE; GENOTOXICITY; CHROMOSOMAL ABERRATIONS; MICRONUCLEI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
B. Dimitrov e P. Gadeva, "GENOTOXICITY STUDIES ON THE INSECTICIDE DURSBAN IN ROOT-MERISTEM CELLS OF CREPIS-CAPILLARIS L", Environmental and experimental botany, 37(2-3), 1997, pp. 199-209

Abstract

Dursban, an insecticide of the organophosphorous group of pesticides,was studied for genotoxicity in plant cells (Crepis capillaris L.) with regard to its ability to induce structural chromosomal aberrations and micronuclei. It was observed that at concentrations comparable to those applied in agricultural practice, Dursban did not induce chromosomal aberrations as estimated by metaphase and anaphase analyses. In the latter case, lagging chromosomes were observed. The frequency of micronuclei (MN) for the Dursban-treated group was statistically significantly increased in comparison with the control: this effect was observed at all concentrations tested. To elucidate the mechanism of MN formation, the micronucleus/macronucleus size ratio was determined. Micronuclei induced by colchicine and gamma-rays were used as controls. Thesize of micronuclei induced by Dursban is similar to that of micronuclei induced by colchicine and significantly larger than that induced by gamma-rays. It was concluded that the formation of micronuclei afterDursban treatment of plant cells was due to partial spindle disturbances, leading to errors in anaphase distribution of the chromosomes, asa result of which some chromosomes appear as lagging ones. (C) 1997 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 22:35:52