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Titolo:
INTERSTITIAL PNEUMONIA LINKED TO FLUOXETINE
Autore:
VANDEZANDE LM; LAMBLIN C; WALLAERT B;
Indirizzi:
HOP CALMETTE,SERV PNEUMOL & IMMUNOALLERGOL,BLVD PR J LECLERCQ F-59037LILLE FRANCE HOP CALMETTE,SERV PNEUMOL & IMMUNOALLERGOL F-59037 LILLE FRANCE
Titolo Testata:
Revue des maladies respiratoires
fascicolo: 4, volume: 14, anno: 1997,
pagine: 327 - 329
SICI:
0761-8425(1997)14:4<327:IPLTF>2.0.ZU;2-C
Fonte:
ISI
Lingua:
FRE
Soggetto:
INDUCED LUNG DAMAGE;
Keywords:
FLUOXETINE (PROZAC(R)); IATROGENIC LUNG DISEASE; DRUG INDUCED LUNG DISEASE; INTERSTITIAL PNEUMONIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
L.M. Vandezande et al., "INTERSTITIAL PNEUMONIA LINKED TO FLUOXETINE", Revue des maladies respiratoires, 14(4), 1997, pp. 327-329

Abstract

Fluoxetine (Prozac(R)) is a new anti-depressant introduced an the marked in France since 1989. We report a case of a patient who developed progressive dyspnea without any other symptoms who had been treated with Prozac(R) for nine months. Clinical examination found bilateral basal crepitations. Laboratory assessments showed evidence of inflammation (ESR : 50 mm per hour; CRP 8.9 mg/l), the pulmonary radiograph and thoracic CT scan showed evidence of bilateral diffused interstitial disease. There was also a restrictive ventilatory defect (TLC 59 per centpredicted; FEV1 79 per cent predicted; FVC 70 per cent predicted), effort hypoxaemia and alveolar hyperlymphocytosis (35 per cent). The clinical, radiological and pulmonary function improved and the bronchoalveolar lavage became normal three months after stopping Prozac(R) suggesting a role for this drug in the genesis of this interstitial pneumonia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:36:23