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Titolo:
REDUCED HOSPITALIZATION WITH CARDIOVASCULAR AND PULMONARY-DISEASE IN OBSTRUCTIVE SLEEP-APNEA PATIENTS ON NASAL CPAP TREATMENT
Autore:
PEKER Y; HEDNER J; JOHANSSON A; BENDE M;
Indirizzi:
SAHLGRENS UNIV HOSP,DEPT PULM MED,SLEEP LAB S-41345 GOTHENBURG SWEDEN SAHLGRENS UNIV HOSP,DEPT CLIN PHARMACOL S-41345 GOTHENBURG SWEDEN CENT HOSP SKOVDE,DEPT MED S-54185 SKOVDE SWEDEN CENT HOSP SKOVDE,DEPT OTORHINOLARYNGOL S-54185 SKOVDE SWEDEN
Titolo Testata:
Sleep
fascicolo: 8, volume: 20, anno: 1997,
pagine: 645 - 653
SICI:
0161-8105(1997)20:8<645:RHWCAP>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITIVE AIRWAY PRESSURE; NOCTURNAL ASTHMA; BLOOD-PRESSURE; HYPERTENSION; ASSOCIATION; MORTALITY; STROKE; MEN;
Keywords:
SLEEP APNEA; CARDIOVASCULAR; MORBIDITY; NCPAP; COST-UTILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
Y. Peker et al., "REDUCED HOSPITALIZATION WITH CARDIOVASCULAR AND PULMONARY-DISEASE IN OBSTRUCTIVE SLEEP-APNEA PATIENTS ON NASAL CPAP TREATMENT", Sleep, 20(8), 1997, pp. 645-653

Abstract

Cardiovascular and pulmonary disease (CVPD) is common in patients with obstructive sleep apnea syndrome (OSAS). This retrospective study addressed the accumulated in-hospital time during 2 years prior to treatment with nasal continuous positive airway pressure (nCPAP) as compared to 2 years after initiating of nCPAP in patients with OSAS and CVPD. A cohort representing all patients (n = 88) receiving nCPAP during the period 1988-1994 at the Skovde Central Hospital, Skovde, Sweden, wasstudied. Data collection was based on interviews with patients as well as reviews of clinic charts. All hospitalizations and diagnostic codes by any type were thereby successfully gathered for the whole group. Six patients with confounding serious diseases were excluded from theanalysis. A CVPD diagnosis (ICD-9, codes 401-435 and 490-496) was found in 54 out of 82 patients (66%), of whom 36 of 58 were nCPAP users (62%) and 18 of 24 were nonusers (75%). In 54 sleep apneics with CVPD, 31 were hospitalized acutely under one or more of these diagnostic codes during the study period of 4 years. The total number of in-hospitaldays due to CVPD in the nCPAP users (n = 19) before nCPAP prescription was 413 days (median 10, range 3-66) compared to 54 days (median 0, range 0-25) after nCPAP (p < 0.0001). The corresponding values for thenonuser group (n = 12) was 137 days (median 8.5, range 0-42) before and 188 days (median 9.5, range 0-47) after the nCPAP prescription (ns). We conclude that nCPAP treatment reduces the need for acute hospitaladmission due to CVPD in patients with OSAS. This reduction of concomitant health care consumption should be taken into consideration when assessing the cost-benefit evaluation of nCPAP therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 19:13:14