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Titolo:
LACK OF COMPLICATIONS FOLLOWING SHORT-TERM STENT THERAPY FOR EXTRAHEPATIC BILE-DUCT STRICTURES IN PRIMARY SCLEROSING CHOLANGITIS
Autore:
DEWIT AWMV; RAUWS EAJ; VANBRACHT J; MULDER CJJ; JONES EA; TYTGAT GNJ; HUIBREGTSE K;
Indirizzi:
UNIV AMSTERDAM,ACAD MED CTR,DEPT GASTROENTEROL,MEIBERGDREEF 9 NL-1105AZ AMSTERDAM NETHERLANDS UNIV AMSTERDAM,ACAD MED CTR,DEPT HEPATOL NL-1105 AZ AMSTERDAM NETHERLANDS RIJNSTATE HOSP ARNHEM NETHERLANDS
Titolo Testata:
Gastrointestinal endoscopy
fascicolo: 4, volume: 46, anno: 1997,
pagine: 344 - 347
SICI:
0016-5107(1997)46:4<344:LOCFSS>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
BILIARY-TRACT STRICTURES; URSODEOXYCHOLIC ACID; MANAGEMENT; LIVER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
A.W.M.V. Dewit et al., "LACK OF COMPLICATIONS FOLLOWING SHORT-TERM STENT THERAPY FOR EXTRAHEPATIC BILE-DUCT STRICTURES IN PRIMARY SCLEROSING CHOLANGITIS", Gastrointestinal endoscopy, 46(4), 1997, pp. 344-347

Abstract

Background: In 10% to 20% of patients with primary sclerosing cholangitis, a dominant stricture of an extrahepatic bile duct is responsiblefor symptoms and an exacerbation of cholestasis. The complications ofa dominant stricture can usually be relieved by endoscopic; placementof a stent through the stricture. The conventional policy of leaving stents in situ for 2 to 3 months is associated with a high incidence (e.g., 50%) of clinical deterioration due to stent occlusion. We have attempted to overcome this problem by substantially reducing the duration of stent placement. Methods: Sixteen patients with symptomatic primary sclerosing cholangitis and dominant extrahepatic bile duct strictures were treated by stent placement for a median interval of only 9 days, Results: In all patients endoscopic stent therapy was technically successful with a 7% incidence of transient procedure-related complications. During median follow-up of 19 months (range 7 to 27 months) serum biochemical evidence of cholestasis decreased substantially and 13 (81%) of the 16 patients became asymptomatic. No patient had a recurrence or exacerbation of either symptoms or biochemical evidence of cholestasis that could be attributed to stent occlusion.Conclusions: Short-term endoscopic stent therapy is a safe and effective treatment for symptomatic dominant extrahepatic bile duct strictures in patients withprimary sclerosing cholangitis.

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Documento generato il 04/04/20 alle ore 02:41:19