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Titolo:
HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 ENVELOPE GLYCOPROTEIN BINDS TO CD8 AS WELL AS TO CD4 MOLECULES ON HUMAN T-CELLS
Autore:
KANEKO H; NEOH LP; TAKEDA N; AKIMOTO H; HISHIKAWA T; HASHIMOTO H; HIROSE S; KARAKI S; TAKIGUCHI M; NAKAUCHI H; KANEKO Y; YAMAMOTO N; SEKIGAWA I;
Indirizzi:
JUNTENDO UNIV,IZU NAGAOKA HOSP,DEPT MED,1129 NAGAOKA IZU NAGAOKA SHIZUOKA 41022 JAPAN JUNTENDO UNIV,SCH MED,DEPT INTERNAL MED & RHEUMATOL,BUNKYO KU TOKYO 113 JAPAN TOKYO MED & DENT UNIV,SCH MED,DEPT MICROBIOL,BUNKYO KU TOKYO 113 JAPAN UNIV TOKYO,INST MED SCI,DEPT TUMOR BIOL,MINATO KU TOKYO 108 JAPAN UNIV TSUKUBA,INST BASIC MED SCI,DEPT IMMUNOL TSUKUBA IBARAKI 305 JAPAN UNIV TSUKUBA,TARA TSUKUBA IBARAKI 305 JAPAN AJINOMOTO CO INC TOKYO 104 JAPAN JUNTENDO UNIV,IZU NAGAOKA HOSP,DEPT MED IZU NAGAOKA SHIZUOKA 41022 JAPAN
Titolo Testata:
Journal of virology
fascicolo: 11, volume: 71, anno: 1997,
pagine: 8918 - 8922
SICI:
0022-538X(1997)71:11<8918:HTEGBT>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECOMBINANT SOLUBLE CD4; HIV-2 INFECTION; LYMPHOCYTES-T; AIDS VIRUS; GP120; RECEPTOR; ACTIVATION; INVITRO; LINES; SIV;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
H. Kaneko et al., "HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 ENVELOPE GLYCOPROTEIN BINDS TO CD8 AS WELL AS TO CD4 MOLECULES ON HUMAN T-CELLS", Journal of virology, 71(11), 1997, pp. 8918-8922

Abstract

We report here that human immunodeficiency virus type 2 (HIV-2) envelope glycoprotein (gp105), but not HTV-1 gp120, can bind to CD8 molecules as well as to CD4 molecules on human T cells. This phenomenon may lead to differences in the life cycles of HIV-1 and HIV-2, and it may be related to the differences in disease manifestations of HIV-1 and HIV-2 infection, including longer survival of HIV-2-infected patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:39:49