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Titolo:
PULSED HOLMIUM LASER-ABLATION OF TISSUE PHANTOMS - CORRELATION BETWEEN BUBBLE FORMATION AND ACOUSTIC TRANSIENTS
Autore:
ASSHAUER T; DELACRETAZ G; JANSEN ED; WELCH AJ; FRENZ M;
Indirizzi:
ECOLE POLYTECH FED LAUSANNE,INST OPT APPL CH-1015 LAUSANNE SWITZERLAND UNIV TEXAS,BIOMED ENGN PROGRAM AUSTIN TX 78712 UNIV BERN,INST ANGEW PHYS CH-3012 BERN SWITZERLAND
Titolo Testata:
Applied physics. B, Lasers and optics
fascicolo: 4-5, volume: 65, anno: 1997,
pagine: 647 - 657
SICI:
0946-2171(1997)65:4-5<647:PHLOTP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
FRAGMENTATION PROCESS; SHOCK-WAVES; INTERVERTEBRAL DISKS; CAVITATION BUBBLES; YAG; GENERATION; INVITRO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
T. Asshauer et al., "PULSED HOLMIUM LASER-ABLATION OF TISSUE PHANTOMS - CORRELATION BETWEEN BUBBLE FORMATION AND ACOUSTIC TRANSIENTS", Applied physics. B, Lasers and optics, 65(4-5), 1997, pp. 647-657

Abstract

Vapor bubble formation and related pressure transients during pulsed holmium laser ablation of tissues are suspected to induce damage. Poly(acrylamide) gels of 70-95% water content with a Young's modulus of 0.14-4.6 x 10(5) Pa served as tissue phantoms to evaluate such effects. Holmium laser pulses (wavelength: 2.12 mu m, duration: 180 mu s FWHM),were delivered through 400 and 600 mu m diameter optical fibers inserted into cubes of clear gel. Bubble effects were investigated using simultaneous flash micro-videography and pressure recording for radiant exposures of 20-382 J/cm(2). Bubble formation and bubble collapse induced pressure transients were observed regardless of phantom stiffness. Bubbles of up to 4.2mm in length were observed in gels with a Young'smodulus of 2.9 x 10(5) Pa at a pulse energy of 650 mJ. An increase ofYoung's modulus (reduction in water content) led to a monotonic reduction of bubble size, In the softest gels, bubble dimensions exceeded those observed in water. Pressure amplitudes at 3 mm decreased from 100/- 14 bars to 17+/-6 bars with increasing Young's modulus over the studied range. Theoretical analysis suggested a major influence on bubble dynamics of the mass and energy transfer through the bubble boundary.

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Documento generato il 02/12/20 alle ore 15:13:22