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Titolo:
PANIC DISORDER, ANXIETY AND DEPRESSION IN RESISTANT HYPERTENSION - A CASE-CONTROL STUDY
Autore:
DAVIES SJC; GHAHRAMANI P; JACKSON PR; HIPPISLEYCOX J; YEO WW; RAMSAY LE;
Indirizzi:
ROYAL HALLAMSHIRE HOSP,DEPT MED & PHARMACOL,SECT CLIN PHARMACOL & THERAPEUT,L FLOOR,GLOSSOP RD SHEFFIELD S10 2JF S YORKSHIRE ENGLAND ROYAL HALLAMSHIRE HOSP,DEPT MED & PHARMACOL,SECT CLIN PHARMACOL & THERAPEUT SHEFFIELD S10 2JF S YORKSHIRE ENGLAND
Titolo Testata:
Journal of hypertension
fascicolo: 10, volume: 15, anno: 1997,
pagine: 1077 - 1082
SICI:
0263-6352(1997)15:10<1077:PDAADI>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
OUTPATIENTS;
Keywords:
HYPERTENSION; PANIC DISORDER; PANIC ATTACKS; DEPRESSION; ANXIETY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
S.J.C. Davies et al., "PANIC DISORDER, ANXIETY AND DEPRESSION IN RESISTANT HYPERTENSION - A CASE-CONTROL STUDY", Journal of hypertension, 15(10), 1997, pp. 1077-1082

Abstract

Background it has been suggested that panic disorder can cause or contribute to hypertension or resistance to antihypertensive drugs, Objective To compare the prevalences of panic disorder, panic attacks, anxiety and depression between patients with resistant hypertension and age-and sex-matched patients with non-resistant hypertension. Design A case-control study of patients attending the Sheffield Hypertension Clinic, using self-completed postal questionnaires to assess panic disorder, anxiety and depression. Patients Cases with resistant hypertensionwere defined as patients who presently or previously had systolic blood pressure above 160 mmHg or diastolic blood pressure above 90 mmHg despite the use of three or more antihypertensive agents at full dose. For each of 136 cases, one control with non-resistant hypertension, defined as controlled to less than or equal to 160/90 mmHg by one or twoantihypertensive agents, was identified by a bias-free method. Cases and controls were matched for age and sex. Main outcome measures Lifetime and current prevalence of panic attacks, the prevalences of panic disorder, anxiety and depression by Hospital Anxiety and Depression Scale scores, and the severity and frequency of panic attacks, Results Of the resistant hypertensive patients, 33% had experienced a panic attack compared with 39% of the control non-resistant hypertensives (resistant non-resistant -6%, 95% confidence interval -19 to +7%), Twelve per cent of the resistant patients and 14% of controls fulfilled the criteria for a current or previous diagnosis of panic disorder (resistant -non-resistant -2%, 95% confidence interval -11 to +7%). There were also no significant differences between the groups in the prevalences of current panic attacks, panic attacks rated as moderate or worse, spontaneous panic attacks and in the frequency of panic attacks. There remained no significant difference between the groups for panic attacksand panic disorder when the analysis was limited to those patients who had idiopathic hypertension. The two groups did not differ significantly in scores for anxiety and depression measured by the Hospital Anxiety and Depression Scale. Conclusion We observed no differences in the prevalences of panic, anxiety and depression between patients with resistant hypertension and non-resistant controls. These factors are probably not implicated in resistance to drug treatment, However, the prevalences of panic disorder and panic attacks were remarkably high in both groups of patients attending a hospital hypertension clinic, The relationship between panic disorder and hypertension deserves further study in a general hypertensive population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 00:30:48