Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
MACROMOLECULAR CONTRAST-MEDIA - A NEW APPROACH FOR CHARACTERIZING BREAST-TUMORS WITH MR-MAMMOGRAPHY
Autore:
DALDRUP HE; ROBERTS TPL; MUHLER A; GOSSMANN A; ROBERTS HC; WENDLAND M; ROSENAU W; BRASCH RC;
Indirizzi:
UNIV MUNSTER,INST KLIN RADIOL,ALBERT SCHWEITZER STR 33 D-48129 MUNSTER GERMANY UNIV CALIF SAN FRANCISCO,DEPT RADIOL,CONTRAST MEDIA LAB SAN FRANCISCOCA 94143 UNIV MAINZ,KLIN POLIKLIN RADIOL D-6500 MAINZ GERMANY BERLEX LABS INC WAYNE NJ 00000 UNIV KLIN KOLN,INST RADIOL DIAGNOST COLOGNE GERMANY UNIV CALIF SAN FRANCISCO,DEPT PATHOL SAN FRANCISCO CA 94143
Titolo Testata:
Radiologe
fascicolo: 9, volume: 37, anno: 1997,
pagine: 733 - 740
SICI:
0033-832X(1997)37:9<733:MC-ANA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
GER
Soggetto:
GD-DTPA; CAPILLARY-PERMEABILITY; GADOLINIUM-DTPA; ENHANCING AGENT; SOLID TUMORS; ENHANCEMENT; ANGIOGENESIS; RATS; DIFFERENTIATION; BIODISTRIBUTION;
Keywords:
MR-MAMMOGRAPHY; MACROMOLECULAR CONTRAST AGENTS; BREAST TUMORS; TISSUE CHARACTERIZATION; MICROVASCULAR PERMEABILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
H.E. Daldrup et al., "MACROMOLECULAR CONTRAST-MEDIA - A NEW APPROACH FOR CHARACTERIZING BREAST-TUMORS WITH MR-MAMMOGRAPHY", Radiologe, 37(9), 1997, pp. 733-740

Abstract

The value of macromolecular contrast agents (MMCM) for the characterization of benign and malignant breast tumors will be demonstrated in this review. Animal studies suggest a high potential of MMCM to increase the specificity of MR-mammography. The concept of tumor differentiation is based on the pathological hyperpermeability of microvessels in malignant tumors. MMCM show a leak into the interstitium of carcinomas, whereas they are confined to the intravascular space in benign tumors. Capabilities and limitations of the MMCM-prototype. Albumin-Gd-DTPA, for breast tumor characterization will be summarized and compared tothe standard low molecular weight contrast agent Cd-DTPA. Initial experience with new MMCM, such as Dendrimers, Gd-DTPA-Polylysine and MS-325 will be outlined. The potential of ''blood-pool''-iron oxides, suchas AMI-227 for the evaluation of tumor microvascular permeabilities will be discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 08:04:41