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Titolo:
HUMAN UTERINE SMOOTH-MUSCLE EXHIBITS A VERY-LOW PHOSPHOCREATINE ATP RATIO AS ASSESSED BY IN-VITRO AND IN-VIVO MEASUREMENTS/
Autore:
STEINGRIMSDOTTIR T; ERICSSON A; FRANCK A; WALDENSTROM A; ULMSTEN U; RONQUIST G;
Indirizzi:
UNIV UPPSALA HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN UNIV UPPSALA HOSP,DEPT OBSTET & GYNECOL S-75185 UPPSALA SWEDEN UNIV UPPSALA HOSP,DEPT DIAGNOST RADIOL S-75185 UPPSALA SWEDEN UMEA UNIV HOSP,DEPT INTERNAL MED S-90185 UMEA SWEDEN UNIV UPPSALA HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN
Titolo Testata:
European journal of clinical investigation
fascicolo: 9, volume: 27, anno: 1997,
pagine: 743 - 749
SICI:
0014-2972(1997)27:9<743:HUSEAV>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR MAGNETIC-RESONANCE; PREGNANT HUMAN UTERUS; INTRACELLULAR PH; SKELETAL-MUSCLE; PHOSPHORUS METABOLITES; ENERGY ECONOMY; IN-VIVO; SPECTROSCOPY; EXERCISE; PARTURITION;
Keywords:
HIGH-ENERGY PHOSPHOCOMPOUNDS; HUMAN UTERUS; MUSCLE; P-31-MRS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
T. Steingrimsdottir et al., "HUMAN UTERINE SMOOTH-MUSCLE EXHIBITS A VERY-LOW PHOSPHOCREATINE ATP RATIO AS ASSESSED BY IN-VITRO AND IN-VIVO MEASUREMENTS/", European journal of clinical investigation, 27(9), 1997, pp. 743-749

Abstract

The purpose of the study was to investigate by in vitro and in vivo methods the phosphocreatine (PCr)/ATP ratio as an expression of the energy metabolic state of human myometrium in comparison with striated skeletal muscle. The contents of PCr and adenylates in biopsies of uterine smooth muscle and m. rectus abdominis from seven term pregnant women were determined in vitro and compared with results obtained in vivo by phosphorus magnetic resonance spectroscopy (P-31-MRS) in the uterusand m. gastrocnemius of eight non-pregnant women. The PCr/ATP ratio in the striated skeletal muscle was about three times higher than that of the myometrium. The results of the in vitro biopsy part of the study and the in vivo P-31-MRS part conformed with each other. In the biopsies both PCr and ATP concentrations were significantly lower in the myometrium than in the rectus muscle, but the difference for PCr was more pronounced, accounting for the significantly lower PCr/ATP ratio inthe uterine smooth muscle. The energy metabolic pattern of uterine smooth muscle differs from that of striated skeletal muscle regarding the contents of high-energy phosphocompounds and the PCr/ATP ratio. Thisin vivo finding is the first report on human smooth muscle using P-31-MRS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:29:18