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Titolo:
ISOLATION AND CHARACTERIZATION OF XENOPUS-LAEVIS XSOX-B1 CDNA
Autore:
SAKAI Y; HIRAOKA Y; KONISHI M; OGAWA M; AISO S;
Indirizzi:
KEIO UNIV,SCH MED,DEPT ANAT,SHINJUKU KU,35 SHINANOMACHI TOKYO 160 JAPAN KEIO UNIV,SCH MED,DEPT ANAT,SHINJUKU KU TOKYO 160 JAPAN KEIO UNIV,SCH MED,DEPT INTERNAL MED,SHINJUKU KU TOKYO 160 JAPAN
Titolo Testata:
Archives of biochemistry and biophysics
fascicolo: 1, volume: 346, anno: 1997,
pagine: 1 - 6
SICI:
0003-9861(1997)346:1<1:IACOXX>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SRY-RELATED GENE; AUTOSOMAL SEX REVERSAL; CAMPOMELIC DYSPLASIA; TRANSCRIPTION FACTOR; DETERMINING REGION; EXPRESSION; DNA; MOUSE; PROTEIN; FAMILY;
Keywords:
DNA BINDING; EMBRYOGENESIS; NUCLEOTIDE SEQUENCE; SOX; SRY (XENOPUS LAEVIS);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
Y. Sakai et al., "ISOLATION AND CHARACTERIZATION OF XENOPUS-LAEVIS XSOX-B1 CDNA", Archives of biochemistry and biophysics, 346(1), 1997, pp. 1-6

Abstract

A family of genes related to the sex-determining region Y gene (SRY) has been termed SOX, and the members are known to encode transcriptional factors and be involved in animal development. We have isolated andsequenced a novel Sox cDNA of Xenopus laevis in this study. The cDNA encodes a protein of 309 amino acids, which encompasses a B-type SOX HMG box; the cDNA was named xSox-B1 in this study. The xSox-B1 mRNA is 1.6 kb in length. Various tissues of adult frog were tested for xSox-B1 mRNA by reverse transcription/polymerase chain reaction, and the results showed that xSox-B1 expression was highly restricted to the ovary. The message of the xSox-B1 gene was also detected in unfertilized eggs and the late blastula embryos of X. laevis. Recombinant polypeptideof the xSox-B1 HMG domain preferentially binds to the AACAAT sequence. (C) 1997 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 18:02:45