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Titolo:
THYMECTOMY FOR MYASTHENIA-GRAVIS
Autore:
GUTH S; NIX HWA; MAYER E; SCHMIEDT W; KRAMM T; MOERSIG W; OELERT H;
Indirizzi:
UNIV MAINZ KLINIKUM,KLIN HERZ THORAX & GEFASSCHIRURG,LANGENBECKSTR 1 D-55101 MAINZ GERMANY
Titolo Testata:
Zentralblatt fur Chirurgie
fascicolo: 8, volume: 122, anno: 1997,
pagine: 655 - 660
SICI:
0044-409X(1997)122:8<655:TFM>2.0.ZU;2-5
Fonte:
ISI
Lingua:
GER
Soggetto:
MAXIMAL THYMECTOMY; THYMOMA; EXPERIENCE; RESECTION;
Keywords:
MYASTHENIA GRAVIS; THYMECTOMY; THYMOMA; FOLLICULAR LYMPHOID HYPERPLASIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
S. Guth et al., "THYMECTOMY FOR MYASTHENIA-GRAVIS", Zentralblatt fur Chirurgie, 122(8), 1997, pp. 655-660

Abstract

Myasthenia gravis is a relatively uncommon antoimmune disorder of neuromuscular transmission. Surgical therapy plays an important role in addition to medical treatment. Follow-up results of 52 patients with thymectomy are presented. Between 1984-1996 thymectomy via median sternotomy was performed in 52 patients with myasthenia gravis (female = 28,male = 24). The score described by Ossermann and Genkins was used forclassification. According to this classification, we found 12 patients in class III, 21 in class IIA, 17 in class IIB and 2 in class III, respectively. A thymoma was found in 19, follicular lymphoid hyperplasia in 24 and an atrophic thymus in 9 cases, respectively. There was no mortality. Severe postoperative complications consisted of bleeding and reoperation in one patient and another patient developed a sternal instability with consecutive operative refixation. Follow-up evaluationafter a mean period of 36 months (min. 6 months, max. 130 months) revealed a relief of myasthenic symptoms in 37 patients. Thymectomy is effective in the treatment of myasthenia gravis with a low complication rate.

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Documento generato il 23/09/20 alle ore 13:06:17