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Titolo:
EOSINOPHILIC ENDOMYOCARDITIS POSTPARTUM
Autore:
GEHRKE D; HERZUM M; SCHONIAN U; KLEIN HH; DRUDE L; MENNEL HD; MAISCH B;
Indirizzi:
PHILIPPS UNIV,ZENTRUM INNERE MED,INNERE MED KARDIOL ABT,BALDINGERSTR 1 D-35033 MARBURG GERMANY UNIV MARBURG,MED ZENTRUM PATHOL,NEUROPATHOL ABT W-3550 MARBURG GERMANY
Titolo Testata:
Herz
fascicolo: 3, volume: 19, anno: 1994,
pagine: 176 - 181
SICI:
0340-9937(1994)19:3<176:EEP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
GER
Soggetto:
MAJOR BASIC-PROTEIN; PERIPARTUM CARDIOMYOPATHY; HYPEREOSINOPHILIC SYNDROME; MYOCARDITIS; DISEASE; PREGNANCY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
D. Gehrke et al., "EOSINOPHILIC ENDOMYOCARDITIS POSTPARTUM", Herz, 19(3), 1994, pp. 176-181

Abstract

We report the case of a 28-year old asthmatic female patient, who developed an acute heart failure beginning with diarrhea, fever, and dyspnea 5 weeks after delivery. After improvement of all vital functions and dismissal from hospital care unit a marked blood hypereosinophilia,left ventricular congestive heart failure, pericardium effusion and fever up to 40-degrees-C followed. Endomycardial, bone marrow and skeletal muscle biopsies and the pericardial fluid showed a marked eosinophilic infiltration or polymyositis, respectively, which could be treated successfully with steroids and azathioprin. During steroid medication cytomegalovirus-associated myocarditis developed and was diagnosed by in situ hybridization. CMV hyperimmunoglobulin treatment (Cytotect(R), Bio-test) was started (2 ml/kg bw on day 1 and 3, and 1 ml/kg on days 5, 7 and 9), which led to the eradication of the residual infiltrate and CMV-DNA in the myocardium. After discontinuation of all medication, eosinophilia and asthma recurred so that immunosuppressive treatment was continued.

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Documento generato il 23/09/20 alle ore 08:03:50