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Titolo:
THE EFFECT OF THE LEVEL OF VENTILATORY ASSIST ON THE LEVEL OF RESPIRATORY DRIVE IN DECEREBRATE CATS
Autore:
MURO S; OKU Y; CHIN KZ; MISHIMA M; OHI M; KUNO K;
Indirizzi:
KYOTO UNIV,DEPT CLIN PHYSIOL,CHEST DIS RES INST,SAKYO KU,53 KAWAHARA CHO,SHOGOIN KYOTO 60601 JAPAN
Titolo Testata:
Respiration physiology
fascicolo: 3, volume: 109, anno: 1997,
pagine: 205 - 217
SICI:
0034-5687(1997)109:3<205:TEOTLO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
NORMOCAPNIC MECHANICAL VENTILATION; INSPIRATORY PRESSURE; MUSCLE-ACTIVITY; FLOW-RATE; HUMANS; SLEEP; INHIBITION; CO2; EXERCISE; SUPPORT;
Keywords:
CONTROL OF BREATHING, CENTRAL DRIVE, ASSISTED VENTILATION; MAMMALS, CAT; MUSCLE, DIAPHRAGM, ASSISTED VENTILATION; PATTERN OF BREATHING, ASSISTED VENTILATION; VENTILATION, ASSISTED, RESPIRATORY DRIVE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
S. Muro et al., "THE EFFECT OF THE LEVEL OF VENTILATORY ASSIST ON THE LEVEL OF RESPIRATORY DRIVE IN DECEREBRATE CATS", Respiration physiology, 109(3), 1997, pp. 205-217

Abstract

The present study was undertaken to investigate whether, independent of changes in Pa-CO2, ventilatory assist influences not only the pattern but also the level of the respiratory drive. The experiments were performed on decerebrate and paralyzed cats ventilated by a phrenic-driven servo respirator at three different FICO2 levels (0, 0.03, 0.05). The level of ventilatory assist was altered within the range where Pa-CO2 did not exceed 80 Torr. A higher FICO2 accompanied a higher level of ventilatory assist. The relationship between the minute phrenic activity and log(10) Pa-CO2 at a given FICO2 was linear. No significant difference was found in the regression lines at different levels of FICO2. We conclude that ventilatory assist has little effect on the respiratory drive at a constant level of chemical feedback during hypercapnia. (C) 1997 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:55:51