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Titolo:
BUPROPION AND SEXUAL FUNCTION - A PLACEBO-CONTROLLED PROSPECTIVE-STUDY ON DIABETIC MEN WITH ERECTILE DYSFUNCTION
Autore:
ROWLAND DL; MYERS L; CULVER A; DAVIDSON JM;
Indirizzi:
VALPARAISO UNIV,DEPT PSYCHOL VALPARAISO IN 46383 CALIF STATE UNIV STANISLAUS,DEPT PSYCHOL TURLOCK CA 95382 STANFORD UNIV,SCH MED,DEPT MOL PHYSIOL STANFORD CA 94305
Titolo Testata:
Journal of clinical psychopharmacology
fascicolo: 5, volume: 17, anno: 1997,
pagine: 350 - 357
SICI:
0271-0749(1997)17:5<350:BASF-A>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE; IMPOTENCE; PENILE; DIAGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
D.L. Rowland et al., "BUPROPION AND SEXUAL FUNCTION - A PLACEBO-CONTROLLED PROSPECTIVE-STUDY ON DIABETIC MEN WITH ERECTILE DYSFUNCTION", Journal of clinical psychopharmacology, 17(5), 1997, pp. 350-357

Abstract

Many antidepressant agents interfere with sexual function. The purpose of this single-blind, prospective study was to determine sexual sideeffects, both positive and negative, of the amino-ketone antidepressant bupropion in a group of nondepressed diabetic men with somatic erectile dysfunction. Fourteen men participated in 10-week protocol consisting sequentially of 2 weeks of baseline testing, 2 weeks of placebo, and 6 weeks of buporpion. Participants also completed daily and weeklyquestionnaires concerning sexual functioning, and a team of investigators rated various dimensions of sexual function every 2 weeks. In addition, a variety of physiologic measures, relevant either to erectile function or to neural/vascular systems during baseline and bupropion treatment. Results indicated that neither subjective nor objective measures of erectile and overall sexual functioning worsened during bupropion. In fact, several measures suggested a trend toward improved sexual functioning. Furthermore, diabetic control was unaffected by bupropion administration. Given the lack of adverse effects on sexual function, along with the potential for improved erectile response, bupropion may provide an attractive choice for the treatment of depression in diabetic men or others for whom sexual dysfunction is a concern.

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Documento generato il 05/07/20 alle ore 03:57:15