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Titolo:
EFFECT OF A THYROID-HORMONE TREATMENT ON BRAIN PROTEIN-SYNTHESIS IN RATS
Autore:
HAYASE K; NAGANUMA Y; MORIYAMA M; YOSHIDA A; YOKOGOSHI H;
Indirizzi:
AICHI UNIV EDUC,DEPT HOME ECON KARIYA AICHI 448 JAPAN AICHI GAKUSEN COLL,DEPT HOME ECON OKAZAKI AICHI 444 JAPAN NAGOYA BUNRI JR COLL,DEPT NUTR & FOOD SCI NAGOYA AICHI 451 JAPAN UNIV SHIZUOKA,SCH FOOD & NUTR SCI,LAB NUTR BIOCHEM SHIZUOKA 422 JAPAN
Titolo Testata:
Bioscience, biotechnology, and biochemistry
fascicolo: 9, volume: 61, anno: 1997,
pagine: 1536 - 1540
SICI:
0916-8451(1997)61:9<1536:EOATTO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC POLYRIBOSOME PROFILES; DIETARY-PROTEIN; SKELETAL-MUSCLE; DIABETIC RATS; TURNOVER; INSULIN; QUALITY; DISAGGREGATION; QUANTITY; GROWTH;
Keywords:
TRIIODOTHYRONINE; PROTEIN SYNTHESIS; BRAIN; RNA ACTIVITY; THYROID HORMONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
K. Hayase et al., "EFFECT OF A THYROID-HORMONE TREATMENT ON BRAIN PROTEIN-SYNTHESIS IN RATS", Bioscience, biotechnology, and biochemistry, 61(9), 1997, pp. 1536-1540

Abstract

The effect of the thyroid hormone on the rate of brain protein synthesis in rats was studied. Experiments were conducted on three groups ofrats given 6-propyl-2-thiouracil (PTU, a thyroid inhibitor) without atriiodothryonine (T-3) treatment, those treated with PTU + T-3, and those treated with neither PTU nor T-3 (control). The fractional rates of protein synthesis in the brain, liver, and kidney of rats given PTU+ T-3 were significantly greater than those in rats given PTU alone. In the brain and kidney, the RNA activity [g of protein synthesized/(gof RNA.d)] were significantly correlated with the fractional rates ofprotein synthesis. In the liver and kidney, the RNA concentration (mgof RNA/g of protein) was related to the fractional rate of protein synthesis. These results suggest that the thryoid hormone treatment would be likely to increase the rate of protein synthesis in the brain of rats, and that the RNA activity is, at least partly, related to the fractional rate of brain protein synthesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 09:53:41